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To Improve The Effective Research Of Music Therapy On Myocardial Ischemia In Rats

Posted on:2014-05-10Degree:MasterType:Thesis
Country:ChinaCandidate:Y W MaFull Text:PDF
GTID:2254330401983377Subject:Physiology
Abstract/Summary:PDF Full Text Request
The ω-hydroxylation product20-hydroxyeicosa-tetraenoic acid (20-HETE) Thispaper studies the effects of music on the impact of myocardial ischemia inrat hearts, the purpose is to prove that music on myocardial ischemia in rats followingthree parameters of a heart two ECG ST segment, three myocardial mechanical index(leftventricular systolic pressure, Left ventricular diastolic pressure, maximal rate, the maximum rate of decrease), if there is improvement in the role. The rats were randomlydivided into three groups,Namely control group, model group (myocardial ischemia),music group (model+music). Control rats: intraperitoneal injection with model group, the same dose of saline, continuous injection three days. Model rats: intraperitoneal injection of isoproterenol (7mg/kg), continuous injection three days. Music rats: intraperitoneal injection of isoproterenol for three consecutive days, a day after the injection ofisoproterenol, and listen to music. Use Chart5acquisition and analysis softwaresimultaneously recorded ECG, heart rate, myocardial mechanical index. The results show that a model group compared with the control group, ST segment depression0.2mv, that the model is successfully established, the music group compared with model group, ST segment increased34.7%.2, model group compared with the control group, heart rate increased by14.9%, compared with the model group music found heart rate decreased by8.5%.3, model group compared with the control group, systolicblood pressure decreased,Diastolic blood pressure, maximal rate of decline, the largest droprate increased, while the music group compared with model group, systolicblood pressure, diastolic blood pressure, the maximum rate of decrease, the maximum no significant difference in the rate of rise.
Keywords/Search Tags:music therapy, myocardial ischemia, myocardial mechanics, heart rate, S-T segment
PDF Full Text Request
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