Anaiysis Of The Risk Factors Of Lower Respiratory Tract Infection Of Childhood Patients With Blood Disease

Objective: To investigate the risk factors of lower respiratory tract infection ofchildhood patients with blood disease. Methods: A retrospective review of the risk factorsof195childhood patients with blood disease in The First teaching Hospital of XinjiangMedical University from June2011to December2012. There were120cases inAL,including60cases with lower respiratory tract infection and60cases without infectionduring the same period. There were75cases in AA,including31cases with lowerrespiratory tract infection and44cases without infection during the same period. Thesignificant factors were identified by single factor analysis. Multi-factors unconditionallogistic regression analysis was conducted. Results: single factor analysis shows differentbetween white blood cell count,homoglobin,vitamin D,neutrophil count,platelet count、cellular immunity(CD3+CD4+CD3+CD8+)was statistically significant within bothgroups(p<0.05),there was no difference in humoral immunity(IgG、 IgA、IgM)level(p<0.05). Multi-factors unconditional logistic regression analysis shows thatwhite blood cell count、neutrophil count、vitamin D、cellular immunity were found asindependent risk factors for lower respiratory tract infection in AL group and AA group.Conclusion: Results in neutrophils,white blood cells,vitamin D,cell-mediated immunity inturn is closely related with acute leukemia in children with lower respiratory tractinfection,cellular immunity,neutrophils,white blood cells,vitamin D turn aplastic anemia inchildren with lower respiratory tract infection closely related,can be targeted to takeprotective measures to prevent the blood child patients with lower respiratory tractinfection occurred.