Distribution Of Candida Albicans In The Oral Cavity Of Children Aged3-5Years Old Of Uygur, Han And Its Gene Type In High Caries Children

Objective: To investigate oral Candida albicans distribution of early childhood cariesamong3-5year old children of Uyghur and Chinese in Urumqi, to explore correlationfactors between early childhood caries and Candida albicans. The aim is to provide datefor caries prevention. Methods: By plaque method to Collect samples of3-5year oldchildren of Uyghur and Chinese in Urumqi, Cultured and identified with CHROMagarCandida medium. By Biochemical and PCR method to appraisal the Candida albicans thatbe cultured. Then Select each20samples of high caries children from each nation, aftersequence to do genotype. Results:(1) The frequence of Candida albicans from Chinese ishigher than that of Urghur.(2) The frequence of Candida albicans from boy is higher thanthat of girl.(3)The frequence of Candida albicans isolated from ECC group is higher thanthat of the non-caries group. The frequence of Candida albicans increased with the dmft’srate. Conclusion: The oral Candida albicans distribution is different in ethnic and genderside. There is a significant association between the presence of Candida albicans andcaries. Candida may be one of the important cariogenic microorganisms. People withCandida albicans genotype type A or type1may be more cariogenic.