Differential And Diagnostic Analysis Of Frequent Thyroid Gland Space-occupying Disease With Multi-slice CT

Objective：Analyzed the non-enhanced and enhanced CT character of thyroid benignand malignant space-occupying disease and had a summary about the different and similaraspect. In order to have some help with the improving of diagnostic agreement. Methods:35cases of thyroid adenoma,284cases of nodular goiter and134cases of thyroidcarcinoma matched the condition that with both pathologic definite diagnosis andcomplete CT data. We reviewed and recorded their character such as size、shape、location、boundary、density、calcification、surrounding and cervical lymph node and so on，and thencompared them. Results: Thyroid adenoma and thyroid carcinoma always were single andnodular goiter always was multiple; Thyroid carcinoma and nodular goiter always locatedat the middle and outside1/3region of the thyroid gland and thyroid adenoma alwayslocated at the middle and inside1/3region of the thyroid gland；Benign focus of infectionalways had smooth borderline while the malignant focus of infection had vague boundaryand narrow transitional zone between the normal gland and disease; The difference onratio of diameter(the maximum diameter of every disease/their vertical diameter)betweenbenign and malignant disease was not statistically significant（P>0.05）. The difference onCT value of solid disease no matter enhanced、non-enhanced or their enhanced extentbetween benign and malignant disease was statistically significant（P<0.05）. Whencompare the CT valve of non-enhanced solid disease with sternocleidomastoid at the sameside, the difference was statistically significant no matter benign or malignant（P<0.05）,but the difference of mean value between the malignant disease and theirsternocleidomastoid at the same side was only3HU. The difference on calcificationbetween benign and malignant disease (especially≤2mm)was statistically significant（P<0.05）. Enlarged cervical lymph node was common seen in our research, but CTdidn’t show any special advantage at the diagnosis of nonage lymph node transplant as other imaging equipment unless there were any typical malignant character. Volumerendering can have a clear show about the relation between the disease and theirsurrounding structure, extrusion or encroach on. Conclusion：There are clear differentabout edge、shape and density between benign and malignant disease, they can be thefoundation of CT diagnosis; as the disease progressing, calcification、lymph node andsurrounding structure can be the valuable factor of CT diagnosis.