| Objective: The aims of this study were to describe the temporal pattern of plasmaN-terminal pro-brain natriuretic peptide in patients between Uygur and Han with acutemyocardial infarction(AMI). To investigate the association of N-terminal pro-brainnatriuretic peptide(NT-proBNP)between left ventricular erection fraction (LVEF) andplasma homocysteine(Hcy)and explore whether there are ethnic differences ofNT-proBNP level. Try to examine the optimum time of sampling with Uygur and Han.Methods: From March2011to February2012, we selected128cases of Uygur Chineseand Han Chinese with AMI, respectively, in the First Affiliated Hospital of XinjiangMedical University. According to race, we divided them into two groups. Measurementsof Hcy and NT-proBNP at0h,14~48h,49~72h, following percutaneous coronaryintervention(PCI), Left ventricular systolic function was assessed after PCI curing sixmonths. Statistic analysis was done with SPSS17.0software. Results: A different patternof plasma NT-proBNP is seen between Uygur and Han, there was significant difference(P＜0.05). NT-proBNP levels were negatively correlated with LVEF. Conclusion:NT-proBNP levels between Han and Uygur groups were significantly different.NT-proBNP at49~72h after PCI of Uygur were independent predictors of pooroutcome.The han patients detection cut-off time set to14~48h. |
