Electro-acupuncture With Sham Acupuncture Learning And Learning Memory Ability In The Behavior Of Rat Model Of Depression

Objective: To observe the electro-acupuncture with sham acupuncture on behavioraland learning and memory ability of rat model of depression. Methods：48SD rats wererandomly divided into a control group， model group， electro-acupuncture group， shamacupuncture group (n=12). Moderate-intensity stimulation applications21d unforeseencombination of a solitary raise stress caused a rat model of depression. At the same timebegan to intervention. The the points of the EA EA group "Baihui" and "YINTANG"，once a day， every15min， a total of21d. Sham acupuncture group were shamacupuncture the Baihui and YINTANG， once a day， every time15min， a total of21days. Blank group without any treatment， the model group modeling only， without anyintervention. Open-Field and sugar consumption experiments rat behavior detection，learning and memory in the Morris water maze test in rats. Results：The model groupcompared with the control group rats， the behavioral test their upright and level ofactivity score were reduced sugar intake percentage reduction and the ability of learningand memory decline; electro-acupuncture group compared with the model group， EAgroup behavior school score higher sucrose consumption was significantly increased (P<0.05); sham acupuncture group compared with the model group， sham acupuncturegroup behavior score and sucrose consumption was no significant increase (P>0.05).Conclusion：Electro-acupuncture treatment can change the21d unforeseen combination ofmoderate-intensity stimulation a solitary raise stress caused rat model of depression，abnormal behavior， sham acupuncture can not be changed.