Clinical And Angiography Characteristics Of Coronary Artery Tortuosity

ObjectiveCoronary tortuosity is a common finding in coronary angiography (CAG), which isassociated with age, female gender and hypertension. The present study was aimed toinvestigate the CAG and clinical features and related risk factors of coronary tortuosity,related factors analysis on coronary artery tortuosity, important significance to revealcoronary distortions in coronary artery disease.Methods：A total of499standard cases who underwent coronary angiography in our departmentduring January1stto June1st2010were enrolled in this study(278male, mean age:62.84±10.13years).Left anterior descending, left circumflex, and right coronary arteries weretraced. Tortuosity was identified by the finding of≥3bends(defined as≥45°change invessel direction)along main truck of at least one artery in diastole. Study population weredivided into tortuosity(n=251)and no tortuosity(n=248)groups. Clinical and angiographiccharacteristics were recorded. All analysis were performed using SPSS13.0software andthe statistically significant exists if P＜0.05.Results：1.comparison of clinical data:251cases(50.30%)involved in the CT group,105male,146female, mean age64.68±9.46years,136cases with a history of hypertension,206cases with coronary heart disease.248cases involved in the non-CT group,173male,75female, mean age60.98±10.46years,114cases with a history of hypertension,204cases with coronary heart disease. Age, blood pressure, blood glucose and ECG changeswere significantly different between the two groups. Systolic pressure in CT group washigher than normal level. There were no significant different in the other indicators amongtwo groups.2.characteristics of coronary tortuosity：the prevalence of tortuosity is50.30%mainly seen in LAD accounting for70.12%, the incidences of single, two, and three ofcoronary lesions were51.0%,42.63%and6.37%. The incidences of mild, moderately and severe tortuosity in LAD were89.77%,10.23%and0.57%. The incidences of mild,moderately and severe tortuosity in LCX were74%,10%and1.33%. Most of the tortuositylocated in mid segment of LAD, distal segment of LCX and mid segment of RCA.Tortuosity rate in LAD was higher than that in others.3. Analysis of coronary tortuosityrisk factors: logistic regression analysis showed that gender, age and mean artery pressurewere independent risk factors for coronary tortuosity.Conclusion:The prevalence of tortuosity is50.30%mainly seen in female patients. Most ofCoronary tortuosity is single-vessel disease，mainly located in mid segment of LAD.Gender，age and mean artery pressure were independent risk factors for coronary tortuosity.