The Correlations Between Sun Exposure Vs. Serum Vit D Level And Bone Density Among Some Menopause Women In Kunming

Objective:This study focuses on the osteoporotic occurrence, bone density and level of bone metabolism found in menopause women who are fully exposed to sunshine in Kunming, and explores the relations between the quantity of exposure and serum Vit D level, bone metabolism indexes and bone density in menopause women, to provide reference dosing for Vit D preparations in prevention and treatment of osteoporosis, and advocates a deeper concern on the clinical study of the osteoporotic occurrence among the people residing in plateau areas.MethodsBased on questionnaires,45menopause women aged over45suffering from secondary postmenopausal osteoporosis were divided into three groups with varied daily sun exposures:Group A, with daily exposure less than30minutes, Group B between30-60minutes and Group C, more than60minutes. A specific check was conducted on each experiment subject for any potential variation in serum Vit D level, related bone metabolism and density.(1) Fasting blood was taken as specimens for metabolic markers and determined with ELISA method for the bone metabolic marker density and with colorimetric method for the calcium and phosphate content in the serum.(2) Bone density was tested by a dual-energy X-ray absorptiometry (DXA) to determine the bone density of the bones from the first to fourth lumbar vertebras and bilateral femoral heads for the resulting T value. (3) A SPSS19.0analysis was conducted on the data collected from each group to determine the statistic significance of their respective data with an analysis of variance and analyze the relations among the groups with χ2testing method.Results:1. Average density values of serum25(OH) D or Vit D in three groups were indicated as follows:19.547ng/ml,29.3158ng/ml and29.8849ng/ml, respectively. The variation found in Group A vs. Group B and C suggests a statistical significance with an average value<0.05, while the variation determined between Group B and C, or P>0.05, was not expected influential.2. A percentage of48.89among the selected45subjects were found having the most optimal serum25(OH)D density level, slightly greater than other plain cities with less sunshine than Kunming.3. Variation in T value in three groups ditto, the variation found in Group A vs. Group B and C suggested a statistical significance with an average value<0.05, while the variation determined between Group B and C, or P>0.05, was not at all influential.4. The osteoporotic occurrence determined in the selected45subjects was35.34%.5. Sun exposure was found correlating positively with serum25(OH)D density but having no identical relevance with bone density.Conclusions:The study indicates the decrease of bone mass in menopause women in local Kunming with an osteoporotic occurrence of35.43%. Of the menopause women selected,48.89%were found reaching the optimal25(OH)D level, slightly higher than their counterparts in plain cities. In addition, sun exposure correlates positively with serum25(OH)D density but suggests no relation with bone density of human body. There being varied causes for bone density, sun exposure doesn’t prove decisive in osteoporotic occurrence.