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Bilateral Breast Cancer Surgery And Radiation Therapy And Has Radiation Dosimetry Comparison

Posted on:2014-07-05Degree:MasterType:Thesis
Country:ChinaCandidate:Y X HanFull Text:PDF
GTID:2254330401480277Subject:Oncology
Abstract/Summary:PDF Full Text Request
Objective:to compare the bilateral breast cancer modified radical surgery on bothsides of chest wall irradiation and points at the same time illuminate different radiotherapydosimetry difference of target and normal tissues and organs, and research to meet therequirements of clinical radiation therapy plan. Methods:18cases were bilateral modifiedradical surgery for bilateral breast cancer patients, using three-dimensional conformalintensity modulated treatment system designed for each patient were bilateral chest wallirradiation and points at the same time two radiation exposure, with the dose distribution,dose volume histogram (dosed volume histograms DVH), the target dose uniformity andnormal tissue, such as lung, heart, are dose to compare two kinds of plan. Results: in bothplans have the same target area of coverage (90%) cases, and bilateral chest wallirradiation time plan comparison, at the same time illuminate V105%from7.6%to4.8%,V110%from0.8%to0.2%, reduced the maximum dose of target area, reducing the PTVaccept high dose irradiation area, in target dose uniformity is better. Both sides of the chestwall irradiation at the same time plan total average hop count (Mus) irradiation plan belowin several times. In normal tissues and organs such as lung, heart, high-dose irradiationvolume (lung V20, V30, V40;heart V30,V40), bilateral chest wall irradiation plan belowpoints time exposure at the same time, there was no statistically significant difference forlow dose irradiation volume. Conclusion: bilateral breast cancer postoperative bilateralchest wall irradiation dosimetry advantage at the same time the main target is to ensurethat coverage under the premise of technology to improve the radiation dose distributionuniformity and reduce the dose of high dose illuminated endanger adjacent organs andvolume, and may reduce treatment time, theoretically able to get bigger gain thantreatment.
Keywords/Search Tags:primazy bilateral breast cancer, Modified radical mastectomy, Intensity-modulated radiation therapy, 3D treatment planning system, Dose volume histogram
PDF Full Text Request
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