Hybrid Single Utility Port Video-assisted Thoracoscopic Surgery Lobectomy For Patients With Early-stage Lung Cancer

Objective:This study is to make a clinical observation of hybrid single utility port video-assisted thoracoscopic surgery (VATS) in the past two years in Tianjin chest hospital, To explore the clinical outcomes of hybrid single utility port video-assisted thoracoscopic surgery (VATS) lobectomy for patients with early-stage lung cancer.Methods:From December2010to June2012,170surgery patients with early-stage lung cancer were collected and divided into the experimental group and the control group, the experimental group was undergone hybrid single utility port VATS lobectomy (95cases) and the control group was undergone simplemini-incision lobectomy (75cases). The general clinical date, perioperative indicators, major postoperative complination and the serum levels of C-reactive protein (CRP) and humoral immunity (IgG、IgA、IgM) of last day before operation or1day,6day after operation were compared between the two groups.Results:(1) By statistical analysis, there were no significance difference in generally clinical date including gender, age, lobectomy, the type of postoperative pathology, the staging of postoperative pathology between the two groups (P>0.05)and the date of the two groups were have comparability.(2) There were statistical differences in incision length (4.68±0.24) cm vs.(10.14±1.54) cm, intraoperative blood lose (173.16±31.56) ml vs.(205.93±39.35) ml,postoperative bed stay(2.52±0.69)d vs.(2.92±0.88)d drainage volume (360.00±61.02)ml vs.(418.93±46.63)ml,drainage tube retention(3.72±0.69) d vs.(4.11±1.01)d,numeric pain intensity scale (5.00±1.06) vs.(6.11±1.23), postoperative inpatient days (9.84±0.92) d vs.(12.07±1.46) d between the two groups (P<0.05). There were no statistical differences in operation time (140.40±28.25) min vs.(134.53±31.11) min, lymph node dissection number (11.43±1.74) vs.(11.12±1.55), and incidence of serious postoperative complications (13.7%vs.24%) between the two groups. The serum levels of C-reactive protein was significantly lower at1day,6day after operation in the experimental group than those of the control group (P<0.05). (3) There were statistical differences in the humoral immunity factors, include IgG, IgA, IgM, at1day,6day after operation between the two groups (P<0.05)Conclusions:Compared with the simple small incision Hybrid single utility port VATS Lobectomy for early stage lung cancer in operative time, surgical difficulty, complete lymphadenectomy was no significant difference in terms of Hybrid single utility port VATS Lobectomy with acute inflammatory reaction to light, trauma, less bleeding, pain, immunity faster recovery, fewer complications, short-term follow-up no deaths, long-term survival needs further follow-up observation. Hybrid single utility port VATS Lobectomy for early lung cancer safe and effective, the treatment of primary lung cancer preferred procedure, and worthy of promotion.