The Changes Of Anterior Chamber Depth, Chamber Angle Width And Intraocular Pressure After Phacoemulsification In Combination With Intraocular Lens Implantation

Objective: The aim of this study is to determine the changes of anterior chamberstructure after phacoemulsification and intraocular lens implantation by ultrasoundbiomicroscopy, and compare the pre-and postoperative intraocular pressures (IOP), andfinally clarify the relationship between IOP with anterior chamber depth and chamberangle width.Methods:87eyes from the63age-related cataract patients in our eye center wereused in this study. Non-contact tonometer and ultrasound biomicroscopy (SW-3200,KINSCAN, SUOER) were used to measure intraocular pressure, central anteriorchamber depth (ACD), the angle opening distance from the scleral500μm (AOD500),and the anterior chamber angle from the scleral500μm (ACA500), respectively, beforeand3months after eye surgery. Paired t-test was used to statistically analyze changes ofthese parameters before and after surgery. Pearson correlation analysis was used toanalyze the statistical significance of the correlation between the changes of intraocularpressure with the changes of ACD, AOD500, and ACA500, respectively. The linearcorrelation was examined by linear regression analysis.Results: The average values of IOP (11.45±2.85) mmHg, ACD (3.96±0.25)mm, AOD500(0.912±0.23) mm, and ACA500(42.11±5.13)°were obtained from87eyes in the patients used in this study3months after surgery. As compared with the datafrom the patients before the surgery: IOP (12.58±2.49) mmHg, ACD (2.28±0.39) mm,AOD500(0.517±0.19) mm, ACA500(23.89±7.54)°, there are statistical differences.Pearson correlation analysis revealed the significant difference between the changes ofACD, AOD500, ACA500and the changes of intraocular pressure (p<0.05), and also theexistence of the negative correlation. The corresponding coefficients were-0.303,-0.316, and-0.260, respectively. The linear regression analysis showed the linear correlation between the ACD, AOD500, and ACA500with IOP, respectively,(p<0.05).Conclusion: Our results indicated that phacoemulsification combined withintraocular lens implantation significantly decreased the IOP after surgery and thatdeepening the anterior chamber and widening the chamber angle ameliorates intraocularaqueous circulation; Our results also showed the negative correlation between the widthof anterior chamber and depth of the chamber angle with the IOP.