Large Intestine Cancer Metastasis Nodules Clinical Pathology Characteristic And Prognosis Of The Correlation

Objective: The clinical significance of the nodules (cancer nodules) has not yetreached a consensus, how classified more reasonable to further study. Clinical practicefound that the poor prognosis of colorectal cancer associated with nodules might rangebetween lymph node metastasis and distant metastasis. This article specificallydiscusses the nodules with clinicopathological features and prognosis of colorectalcancer associated with cancer.Methods: Retrospective analysis of the First Affiliated Hospital of DalianMedical University, General Surgery from January2002to December2006were1036cases of colorectal cancer patients with clinical and pathological data, includingpathological findings showed nodules, a total of56cases, accounting for5.4%(56/1036), including the number of nodules, gender, age, tumor size, tumordifferentiation, tumor type, tumor morphology, tumor location, depth of invasion,pathologic stage and carcinoembryonic antigen (CEA) and other information,.Statistical analysis using IBM SPSS statistics software on the computer for processingand the establishment of a database, IBM SPSS19.0descriptive analysis of the numberof nodules and gender, age, tumor type, tumor size, tumor location, tumordifferentiation, using non-parametric tests, depth of invasion, lymph node metastasis,distant metastasis, staging and carcinoembryonic antigen (CEA) of the relationship.Survival analysis using the kaplan-Meier method was (all the results of taking P <0.05statistically significant). TNM and pathological staging according to AJCC SeventhEdition tumor staging manual.Results:56patients with colorectal cancer were detected in70nodules, with anaverage of1.08, nodules, the number one of42patients,14cases more than one;primary adenocarcinoma (high degree of tumor differentiationdifferentiation3; differentiation30cases; poorly differentiated,11cases);9cases of mucinousadenocarcinoma; other types of three cases; confirmed by pathology, the primary tumorand the degree of differentiation of cancer nodules; tumor shape ulcer47cases; uplifttwo cases; the fungating7cases; TNM staging of invasion and deep myometrial threecases; serosa of53cases;14cases without lymph node metastasis,42cases with lymphnode metastasis; no distant metastasis42cases,14cases with distant metastasis. Thedata show that patients with pathologic stage in stage Ⅱ14cases; III of28patients; IVof14patients. The statistics show that the nodules, with or without gender, age, tumortype, tumor size, tumor location, tumor differentiation, depth of invasion, distantmetastasis and pathological stage were not statistically different; this group of patientsby statistical data analysis, and nodules, number of lymph node metastasis, and CEAwas statistically significant (all P <0.05)..Conclusion: Non-parametric test results suggest that the nodules associated withcolorectal cancer patients and patients with non-cancerous nodules in the lymph nodemetastasis was statistically significant, with distant metastasis was no significantdifference, suggesting that the source of the nodules with lymph node metastasisrelatedrather than due to distant metastasis and poor prognosis, its clinical significance issimilar to the lymph node metastasis.