Epidemiology Of Diabetes In Rural Shaanxi Province And Regional Difference Of Diabetes Between Coastal And Interior Provinces In China

Study1: Epidemiology of Diabetes in Rural Shaanxi ProvinceThe prevalence of diabetes in low-and middle income area, such as rural country, has beenincreasing and evoked worldwide focus. However, well-designed cross-sectional survey in ruralShaanxi province was lacked in the past decade.ObjectiveTo investigate the prevalence of diabetes, addition with its cardiovascular risk factors(hypertension and dyslipidemia) in rural Shaanxi province.MethodsThe data were from the China National Diabetes and Metabolic Disorders Study2007-08.Withstratified cluster sampling method,1191rural adults aged above20years were included asparticipants in Shaanxi province from August,2007to June,2008. Standardized questionnaire wasused to obtain demographic information, lifestyle risk factors and family history. All participantswere administered a glucose tolerance test and laboratory examination. ResultsThe age-standardized prevalence of diabetes was7.29%. Ag（eOR:2.007,95%CI:1.640-2.455）,physical activities (OR:1.615,95%CI:1.002-2.603) and central obesity (OR:1.981,95%CI:1.205-3.259) were independently associated with diabetes prevalence. The age-standardizedprevalence of hypertension was29.08%. Age (OR:2.265,95%CI:1.997-2.568), central obesity(OR:2.033,95%CI:1.515-2.729) and family history (OR:1.717,95%CI:1.285-2.295) wereindependently associated with hypertension prevalence. The age-standardized prevalence ofdyslipidemia was32.11%. Age (OR:1.140,95%CI:1.029-1.263), cigarette smoking (OR:1.680,95%CI:1.263-2.235), physical activities (OR:1.329,95%CI:1.000-1.766) and central obesity(OR:2.033,95%CI:1.515-2.729) were independently associated with dyslipidemia prevalence.ConclusionDiabetes, hypertension and dyslipidemia are common in rural Shaanxi province and the riskfactors of the three diseases are distinct from those in general population.Study2: Regional differences in diabetes prevalence and awarenessbetween coastal and interior provinces in China: a population-basedcross-sectional studyDiabetes prevalence shows a geographical difference all over the world in previous studies.Most studies on diabetes prevalence and awareness in China are regional or about a singleprovince, and differences between coastal and interior provinces have not been discussed even inthe nation-based studies.ObjectiveTo determine regional differences in diabetes prevalence and awareness between coastal andinterior provinces, and to identify the factors associated with diabetes prevalence and awareness.MethodsProvinces Fujian and Shaanxi were chosen to represent the coastal and interior provinces,respectively. The data of two provinces were from the China National Diabetes and MetabolicDisorders Study2007-08. A total of5926people (Fujian2672and Shaanxi3254) aged above20 years were included as participants in the study. Age-standardized prevalence and awareness werecompared between provinces. Logistic regression analysis was performed not only to examine riskfactors of diabetes prevalence and awareness, but also to examine the association between regionaldifference and diabetes prevalence and awareness.ResultsThe age-standardized prevalence of diabetes in Fujian was higher than that in Shaanxi amongtotal (11.5%vs.8.0%), male (13.6%vs.8.9%) and female (10.8%vs.7.4%) populations. Diabetesawareness for total and male population in Fujian was higher than that in Shaanxi (42.3%vs.34.9%and46.8%vs.35.2%, respectively). Age, sex, central obesity, family history of diabetes,and metabolic risk factors were all significantly associated with diabetes prevalence in bothprovinces. However, cigarette smoking was significantly associated with prevalence in Fujian andphysical activity was significantly associated with the prevalence in Shaanxi. Family history ofdiabetes was the only independent risk factor of awareness in both provinces. After being adjustedfor all listed risk factors, the regional difference of diabetes prevalence was still significant, butthat of diabetes awareness lost significance.ConclusionsBoth diabetes prevalence and awareness were higher in coastal provinces and lower in interiorprovinces in China. Lifestyle risk factors were found to contribute differently to diabetesprevalence in the two provinces and other unknown risk factors may account for differences ofdiabetes prevalence between provinces. In addition, family history of diabetes was the onlyindependent risk factor in both provinces.