Effects Of Phytosterols On The Growth Performance, Blood Parameters And Antioxidant Capacity Of PIGS

The study was conducted to investigate and compare the effects of different phytosterols levels in ration on the growth performance, the blood parameters, the antioxidant capacity of pigs by administration of different levels of phytosterols. The results would provide the scientific basis for a reasonable choice between different phytosterols levels of feed in pig production. This study included three experiments:In trial1, the effects of different phytosterols levels in ration on the growth performance of weaned pigs and growing pigs and exploring the addition of phytosterols in the high-dose level, whether weaned pigs and growing pigs have adverse reactions. One hundred ninety-two28-day-old weaned pigs were randomly divided into four experimental groups, every group had six replicates, and there were eight pigs for each replicates. These weaned pigs were average initial body weight7.46±0.64kg. Control group fed a diet without phytosterols supplementation and experimental diets supplemented with:30mg/kg phytosterols (PSI),150mg/kg phytosterols (PSII) or300mg/kg phytosterols (PSIII). The trial was conducted for two periods:the starter(28-56d) and the latter period(57-82d). The results showed that, In the starter period, the treatments which added different phytosterols increased the level of ADG to3.59%,4.42%and2.52%(P>0.05) of the starter period compared with control groups. In the starter period, PSII group significantly decreased the level of ADFI (P<0.05) compared with control and PSI groups. PSIII group also significantly decreased the level of ADFI (P<0.05) compared with PSI groups. In the latter period, the treatments which added PS didn’t affect total gain, ADG, ADFI or F/G of growth performance (P>0.05) compared with control group; The groups added different levels PS didn’t affect the diarrhea, mortality and organ indexes (P>0.05).In trial2, the effects of different phytosterols Revels in ration on the blood parameters of weaned pigs and growing pigs. The treatments were the same as that of trial1. The trial was conducted54d. the starter (28-56d) and the latter period (57-82d). In the starter period, the results showed that The PSII group significantly decreased the level of PLT and PCT (P<0.05) compared with control groups, The PSIII group significantly increased the level of HCT(P<0.05). There was no difference on ALT, ALP, ALB, CRE, GLU of blood biochemical parameters (P>0.05) in the group which added different levels PS. However the PSI groups significantly decreased TP (P<0.05) and the PSⅠ, PSⅡ, PSⅢ groups significantly decreased UN (P<0.05). The PSII groups significantly decreased TC27.65%compared with control groups (P<0.05). The groups added PS increased the LDL-C to50.51%,79.80%and65.66%, compared with control groups (P<0.05). In the latter period, the PSI group significantly increased the blood HCT30.17%, but the PSⅠ, PSⅡ, PSⅢ groups didn’t affect the other blood routine indicators such as WBC, LY, RBC, HGB, PLT and PCT (P>0.05) compared with control group; the PSⅠ、PSⅡ、PSⅢ groups different increased the HDL-C71.45%(P<0.05),18.28%(P>0.05) and14.30%(P>0.05) compared with control group; the PSI group decreased LDL-C25.73%(P>0.05) and the PSIII group significantly decreased LDL-C54.29%(P<0.05) compared with control group.In trial3, the effects of different phytosterols levels in ration on the antioxidant capacity of weaned pigs and growing pigs. The treatments were the same as that of trial1. The trial was conducted54d. the starter (28-56d) and the latter period (57-82d). In the starter period, the results showed that the PSI group decreased the blood and hepatic MDA activity and increased the blood and hepatic T-SOD, GSH-Px activity(P>0.05). In the latter period, In this period, the PSⅠ, PSⅡ, PSⅢ group didn’t affect the blood antioxidant capacity (P>0.05) and increased the hepatic CAT and GSH-Px activity (P>0.05)In conclusion, by increasing PS distribution, the improvement in growth performance, indicators of fat metabolism and antioxidant capacity of the weaned pigs and growing pigs. Considering of the economic and experimental results, we prospected that amount of30mg/kg PS added for weaned and growing pigs were better.