| Objective The purpose of this study was to find an accurate, objective and simple measurement method by applying Digital image processing technology and Endoscope Assistant software which specially develop for endoscopeMethods1. Panaroma tool software employed to correct barrel distortion of endoscopy whereas Image J software used to measure lesion size and the relative measurement error:1. To establish the method of computer softwar measurement to Endoscopic lesions area in vitro, First, Identify correction factor of Panorama tool to minimize measurement error; And then to observe influence of change of endoscopy object distance between the lens and the image.2. To use computer software to measure gastric ulcer area of50patients and compare the difference between the computer image analysis method and the traditional formula method;2.(1) Based on the work program was expected to be completed, the program set the three modules, that was barrel distortion correction, perspective transformation, the transformation of the area, the use of C++language with the Qt database made Endoscope Assistant, Software(EAS);(2) in vitro to establish the template of concentric circles of different object distance is used to verify the reliability and repeatability of EAS;(3)45cases of patients with gastric ulcer lesion area were measured by EAS Results1.(1). Choose0.1as correction factor for barrel distortion of endoscopy;(2) Previous to the correction of the barrel distortion, the relative error of measurement gradually increased with the increasing distance of endoscopy and the image. However, different object distances did not exert influence on the relative measurement error when barrel distortion was corrected by Panaroma tool (P=0.141).3). With the application of the computer software technology to measure50patients with gastric ulcer and the combinational treatment of Panorama tool and Image J software, the results showed that the ulcer area (35.0mm2±5.0mm2) after the treatment of Panorama tool and Image J software was larger than that of the traditional formula method calculated the area (29.1mm2±4.1mm2). The difference was statistically significant (P=0.000), with a correlation coefficient of0.988;2.(1)Relative measurement error was less than6%on different object distance after correction by EAS, different object distances did not exert influence on the relative measurement error when barrel distortion was corrected by EAS (P=0.323)(2)With the application of the EAS to measure45patients with gastric ulcer,the results showed that the ulcer area (44.0mm2±37.0mm2) after the treatment of EAS was larger than that of the traditional formula method calculated the area (36.1mm2±31.4mm2). The difference was statistically significant (P=0.000), with a correlation coefficient of0.990; and the measurement of ulcer areas by the EAS method and Panorama tool and Image J software(41.2mm2±30.9mm2)ware no significant difference (P=0.397).Conclusion We use digital image processing software as known and independently developed EAS to measure the area of endoscopic ulcer, as a result, in vivo test, digital image processing technology of measurement is feasibility and accuracy, and the EAS have achieved the integration of barrel distortion correction of endoscopic images and area measurement functions, the EAS is expected for the industrialization, the EAS is relatively accurate, objective and simple, economical and practical for clinical measurement techniques. |
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