| Growth in intracranial tumors known as brain tumors, including primary brain tumors in the brain parenchyma, meninges, pituitary gland, cranial nerves, cerebrovascular and remnants of embryonic tissue and tissues of malignant tumors in other organs of the body transferred to the cranialwithin the secondary brain tumor. Brain tumors occur in a limited volume of intracranial invasive Whether benign or malignant, will produce the surrounding normal brain tissue compression or injury. Caused by increased intracranial pressure, the corresponding function and nerve damage, and even life-threatening. Not only endanger the lives of patients with brain tumors occurred, but also because of the damage to the nerve function, seriously affecting the quality of life of patients. Western medicine treatment of brain tumors include surgery, radiotherapy, chemotherapy. Whether it is a single surgical treatment, or multi-channel combination therapy, although you can lift the oppression of the tumor on the brain, but in control of a brain tumor at the same time inevitably damage to normal brain tissue, easy to damage the central nervous system and functional areas, or brain edema after radiotherapy and after radiotherapy side effects, leading to a serious decline in quality of life after treatment. Traditional Chinese Medicine can not destroy solid tumors, but have their own unique advantages to reduce the clinical symptoms and improve prognosis. Chinese medicine believes that the characteristics of the pathogenesis of brain tumors can be summarized as righteousness deficiency, phlegm, qi stagnation, blood stasis, wind, fire, drug interactions, long time, accumulate in the brain made tangible mass. Medicine on the basis of rousing governance phlegm and blood stasis, qi and blood circulation, detoxification expelling wind. Chinese medicine treatment of brain tumors advantage to improve the clinical symptoms, reduce cerebral edema after surgery, to reduce the side effects of radiotherapy and chemotherapy, improve patient quality of life and prolong survival. The clinical observation is a prospective clinical study, we observed the clinical efficacy of Chinese medicine Erchen combined Western medicine treatment of patients with primary brain tumors.Objective:Observe the effect of Er Chen Tang Clinical Modified combined Western medicine treatment of patients with primary brain tumors, clinical efficacy, and western medicine control group the efficacy of symptoms, a six-month survival rate.Mathods:According to a certain diagnosis, inclusion and exclusion criteria, standards-compliant cases,75cases collected during October2011-March2013Guang An Men Hospital of China Academy of Traditional Chinese Medicine oncology and Capital Medical University Affiliated Beijing Millennium Monument Hospital inpatient and outpatient settings,all into the group of patients were treated with routine western medicine intreatment group and45patients in the control group of30patients. Treatment group, while in the conventional Western medicine treatment Clinical application of Chinese herbal medicine Erchen Treating brain tumors,14-day course of treatment, even served six courses (3months), according to the clinical part of the stroke clinical neurological deficit scores standard and the U.S. National Institutes of Health stroke Scale (NIH stroke scale, NIHSS), group evaluation and group evaluation methods, evaluation of treatment before and after improvement of clinical symptoms, progression-free survival and survival of six months.Results:Improvement of clinical symptoms Evaluation:According to the clinical part of the stroke patients with nerve function defect scores and the United States National Institutes of Health Stroke Scale (NIH Stroke Scale, NIHSS) score results showed that:the treatment of neurological deficit scores:before treatment4.73±5.92after treatment was3.16±4.95, P<0.05, the difference was statistically significant. Chinese Erchen combined Western medicine in the treatment of primary brain tumors can improve the degree of neurologic impairment; degree of neurological deficit score difference between the two groups of control group after3months of treatment, the treatment group difference of1.58±2.29, control group difference of0.53±1.38, P<0.05, the difference was statistically significant. Chinese medicine Erchen combined Western medicine treatment is better than Western medicine alone in improving patients with neurological deficits. Before and after treatment NIHSS score compared with pre-treatment NIHSS value of4.13±4.46, the treatment NHISS value of3.97±3.40, P<0.05, the difference was statistically significant. Erchen of the application of traditional Chinese medicine treatment of primary brain tumors is effective in improving the clinical symptoms. NIHSS comparing the difference between the treatment group and control group before and after treatment, NIHSS difference of treatment group1.42±1.72, the difference between the control group NIHSS0.67±1.38,P<0.05, the difference was statistically significant. Application of Chinese medicine Erchen combined Western medicine treatment of primary brain tumors is effective in improving the clinical symptoms than Western medicine treatment group.Conclusion:Clinical Modified combined Western medicine in traditional Chinese medicine Erchen the clinical efficacy of the treatment of patients with primary brain tumors better than western medicine treatment of patients with traditional Chinese medicine to improve neurological deficits and clinical symptoms of primary brain tumors have a certain effect, can improvethe patient’s quality of life. |
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