The Children Allergic Purpura Type Distribution And Immune Correlation Studies

Objective: Analysis allergic purpura (HSP) Chinese medicine diagnosis andclassification and peripheral T lymphocytes subsets, food allergens andperipheral blood platelet count of white blood cells and the correlation. Fromthe cell level in the acute phase of children of the HSP discuss TCM syndrometype and the related laboratory relationship, for the treatment of HSP providestechnical parameters, the syndrome differentiation and treatment has certainparting significance.Methods:1. Clinical research methods: the simple prospective randomizedtrials, in line with the criteria of84cases of, at the same time, a group of30cases of health; The common higher education reference of traditional Chinesemedicine JingBian textbook the pediatrics of traditional Chinese medicine ofpatients to study TCM syndrome differentiation type points.2. Experimentaldetection methods: the immune fluorescence method to detect peripheral Tlymphocytes and group (CD3~+, CD4~+, CD8~+, CD4~+/CD8~+); The in vitro qualitativeenzyme immune analysis detection food allergens; The electrical resistance andhigh frequency electric conductance and laser scattering joint test detectionof white blood cells and peripheral blood platelet count.3. Statistical methods:the SPSS17.0for Windows statistical package data processing analysis.Result:1.84cases in the acute phase of children of the HSP TCM syndrome typedistribution to wind hot injury type winding most (53.6%), followed by hot andhumid bi resistance type (36.9%), other card type less (9.5%).2. CD4~+, CD4~+/CD8~+HSP group and health group was significant difference(P﹤0.01); CD3~+, CD8~+health group compared with no significant difference(P>0.05); T lymphocyte subsets in HSP wind hot injury type winding with hotand humid bi resistance between type is no significant difference (P>0.05);T lymphocyte subsets in the acute phase of recovery and HSP no significant difference (P>0.05).3. HSP children food allergens was78.57%detection, different kinds of positivefood allergens are: the seafood (19.05%), milk (15.48%), eggs (13.10%), meat(11.90%) and wheat (10.71%), peanut soybean (8.33%). All kinds of allergens inthe wind hot injury type winding and attack the distribution of damp and hotresistance type no significant difference (P>0.05).4. Peripheral white blood count in the HSP wind hot injury type winding withhot and humid bi resistance between type with significant difference (P﹤0.01);Platelet count in between two card type no significant difference (P﹥0.05).Conclusion:1. Allergic purpura in the acute phase of children of the TCMsyndrome type distribution to wind hot injury type winding, hot and humid biresistance type which is being seen.2. Allergic purpura in the acute phase of children of the existing cellular immunefunction disorder, mainly displays in CD4~+, CD4~+/CD8~+is decreased obviously.3. Seafood and milk is the main food allergens. All kinds of allergens in theHSP the acute phase of TCM syndrome type distribution no significant differences.4. Peripheral blood platelet count of white blood cells, the acute phase hasincreased in HSP trend. Peripheral white blood count in the HSP wind hot injurytype winding is hot and humid bi resistance type significantly higher; Plateletcount in between two card type no significant differences.