| Knee osteoarthritis (KOA) is a common and difficulty-occuring disease in orthopaedic, that happens at40-65years old, more women than men.This disease is difficult, had a long, difficult treatment, that made the old people in low quality, economic losses and lead to long-term disability is one of the main diseases. Because of knee OA is a degenerative disease, its degeneration process irreversible, at present there is no effective way to cure clinically. Relieve symptoms in patients with osteoarthritis, slow knee progressive degeneration process of OA become now to be desired. External treatment of traditional Chinese medicine in the treatment of knee osteoarthritis has its unique advantages, can make the drugs and the physical stimulation direct role in trouble place, make to the efficacy of illness, treatment more targeted, and there are simple and feasible, the characteristics of small side effects.Low frequency ultrasound is now the third administration way, in the drug through skin has its unique advantage. This subject adopts low frequency ultrasound treatment knee OA, according to randomized, double-blind, controlled clinical observation of the research method, evaluation and treatment of traditional Chinese medicine low frequency ultrasound through the efficacy and safety of the knees OA. And through the animal experiment of low frequency ultrasound to promote through further in-depth study of the role, through the low frequency ultrasonography in traditional Chinese medicine and role of large molecules through observation, further proof of ultrasonic through skin to the mechanism of action of medicine, for clinical research provide more scientific objective basis. |