Clinical Characteristics And 50 Cases Of Early Diabetic Nephropathy Tcm Syndrome

The analysis on the epidemiology of type2diabetes in recent years, shows that the incidence of type2diabetes is increasing year by year, and China may become the country with the largest population of type2diabetes, followed by complications increasing. Diabetic nephropathy is one of the microvascular complications of diabetes, cause of death row after cardiovascular and cerebrovascular complications. According to Mogensen staging, the early diabetic nephropathy (Ⅲ period) can be reversed, so earlier aggressive treatment can help to improve the prognosis of patients with diabetic nephropathy, and delay renal failure, in which traditional Chinese medicine(TCM) played an important role. However, due to the subjectivity of TCM, and the syndrome differentiation is not yet unified, it is still lack of broad consensus on early diabetic nephropathy of TCM. So speed up the study of early diabetic nephropathy syndrome characteristics, and explore correlations between syndromes and modern physical and chemical indicators can play a guiding significance. This study collected a total of50cases of early diabetic nephropathy patients to explore the characteristics of main syndrome and complicated syndrome, and try to research its relationship with some of the physical and chemical indicators.Objective:Analysis and summarize the distribution of syndrome in Type2diabetes mellitus in early diabetic nephropathy (Mogensen, the stage III), to explore the characteristics of diagnosis and treatment on type2diabetes mellitus early diabetic nephropathy, provide a useful reference for the TCM of early diabetic nephropathy Syndrome.Method:Collected the general and clinical data of50cases of type2diabetes with early diabetic nephropathy (Mogensen, the stage III) from the hospitalized patients in TCM ward, which from Ministry of Health Beijing Hospital of Traditional Chinese Medicine during January2011to February2012.Then summary and analysis the clinical features and TCM syndrome distribution characteristics of type2diabetes mellitus in early diabetic nephropathy.Result:In these collected50cases, older than65years of age cases accounted for54%, overweight and obese patients accounted for80%,54%with diabetic retinopathy,72%with diabetic peripheral neuropathy, diabetes peripheral vascular disease accounted for80%.82%combined with hypertension,70%with dysl ipidemia,44%with coronary heart disease, cerebrovascular disease accounted for14%. Taking the constituent ratio of each syndrome as a point of view, in the main syndromes of early DN, the primary one both qi and yin deficiency is accounted for48%; in the complicated syndrome the blood stasis is accounted for46%. Among the three main syndromes, there are no significant differences in diabetes complications hypertension, coronary heart disease,but in dyslipidemia are significantly difference(P=0.038). In complicated syndromes, these are no significantly differences.There are no significant differences in the main and complicated syndromes on physical and chemical indicators, including body mass index, serum urea nitrogen, serum creatinine, total cholesterol, triglycerides, urinary albumin excretion rate, estimated glomerular filtration rate.Conclusion:Through the analysis and induction, it prompts①the aging, overweight and obesity probably are risk factors of early DN.②most early DN combine with other diabetic microvascular disease, particularly in diabetic peripheral neuropathy.③most early DN combine with other diabetic vessel pathological changes.④early DN is easier to complicate with hypertension and dyslipidemia.⑤As to the constituent ratio of early DN syndromes, the both qi and yin deficiency and blood stasis take a primary station, which matches the pasr study.⑥TCM sydromyes reflect the entire pattern, but patients’symptoms and the syndromes are different, specific to the patient should be individualized.