Based On Modern Literature And Clinical Research Of Generalized Anxiety Syndrome And Syndrome Factors Of Tcm Research

Purpose: At present, the TCM syndromes of anxiety disorders in the dialectical method is not yet unified, Range of card type, Even the country, industry or professional established by the Committee on the anxiety disorder syndrome type are not standardized, and unity, so that the clinical efficacy and development of Chinese medicine for anxiety disorders has been a serious constraint. In recent years, growing number of clinical reports of anxiety disorders, However, because of the lack of a unified TCM sub-standard, or similar to card type a different name, or the card type with similar names but different in content, or dialectical point can hardly be understood by clinicians and mastermakes. TCM syndrome type of anxiety disorder is difficult to get unified, the clinical efficacy of outreach and awareness are also affected. This study is a retrospective col lection and analysis by the climate literature of TCM with generalized anxiety by the help of modern statistical methods, and research the symptoms and syndrome factors of patients with general ized anxiety in clinical research of TCM, Explore the distribution of characteristics of the syndrome, and syndrome elements about the generalized anxiety, Actively promote the study of the etiology and pathogenesis of anxiety disorders, and provide reference in further study for syndromes standardization of this disease.Methods:1. Literature research:To searching the Climate-related literature of the retrieve anxiety disorders of TCM in National Knowledge Infrastructure (CNKI).The included in the literature is divided into two types:TCM syndromes related literature and Treatment of the literature. The original information and data to quantify the input into the computer and the type of each syndrome as a record entry. Import the data into the statistical software of SPSS17.0, statistics the frequency statistics of the climate syndrome factors.2. Clinical research:Selected200cases of the Dong Fang Hospital of Beijing University of Traditional Chinese Medicine in January2007to2011in November and met the inclusion criteria of patients with generalized anxiety disorder, Fill in traditional Chinese medicine syndrome factor questionnaire, met the inclusion criteria by two deputy director of the above titles MD, the professionals of psychological evaluation judgments the patients with Generalized Anxiety by the HAMA and HAMD. The relevant data will be digitized into the computer, establish a database by the statistical package of SPSS17.0for descriptive analysis, correlation analysis.Results:1. Literature research:(1) TCM syndromes related literature:Retrieved36TCM syndromes related literatures, after induction, the literatures of syndrome type are54. The syndromes of frequency of more than10are6, followed by Liver qi stagnation,Heart deficiency, Phlegm interference, Heart and spleen deficiency, Qi transformed to fire.21syndrome elements in the literature, There are six disease locations syndrome factors, Frequency more than5%are heart, liver, kidney, spleen, gall bladder.15pathogenesis pathogenic class syndrome factors, Frequency of more than5%are Qi stagnation, The fiery, Qi deficiency, Yin deficiency, Sputum, Blood deficiency.(2) Literature of the single method: Retrieved23Treatment of the literature, The syndromes grouped into11, frequency more than10%of the syndromes followed by Qi transformed to fire, Imbalance between heart and kidney, Phlegm interference. There are14syndrome factors in the basis of party literature, disease locations syndrome factor of5, frequency of more than5%followed by the heart, liver and kidney. There are9Pathogenesis, disease resistance syndrome factors, the frequency of occurrence in more than5%of the Hot, Qi stagnation, Yin deficiency. Retrieved23squares in the literature, the treatment method belongs to a class, but statements are not the same be summarized as a class were grouped into15categories. And statistics the drugs,12herbal medicine in a higher frequency.2.Clinical research:Statistics of200cases of patients with generalized anxiety symptoms appear, followed by descending the top ten symptoms of irritability, depressed mood, chest tightness and like heave a deep sigh, fatigue, palpitation and more dream, short breath, sleepy head and body weight, lazy words, dry mouth and throat, mouth pain. Statistical syndromes elements, descending order of Qi stagnation, Qi deficiency, The fiery, Blood deficiency, Yin deficiency, Phlegm syndrome, Blood stasis. In200cases of generalized anxiety patients,16cases of pure empirical (8%),15cases of pure deficiency (7.5%),169cases of false is mixed card (84.5%). Syndrome elements of the merger, two, three, four, five cards combined is most prevalent. According to the clustering results, seven syndrome elements were clustered into two categories, can be a deficiency, hot, phlegm syndrome, qi deficiency, qi stagnation, yin deficiency were clustered into one class, blood stasis is another class. Statistics HAMA score of200cases of patients with generalized anxiety. In200patients,197cases belong to14-21minutes, that is certainly anxiety, accounting for98.5%; only three cases belong to22-29points, namely, anxiety, accounting for1.5%To do spearman correlation analysis between syndrome elements and HAMA score, we can see, the elements of traditional Chinese medicine syndrome "Qi stagnation" and "Qi deficiency" with HAMA score was positively correlated (P<0.05).Conclusion:1. Literature research:(1) Af ter the54kinds of syndrome type of specifications, except for the six kinds of syndrome type appears in frequency of more than10times, the remaining48kinds of syndrome types were appeared10times, seen the distribution is very dispersed, which frequency times for the1of syndrome type there are21kinds.(2)the cumulative percentage of the syndrome factors are more than a cumulative percentage (50.2%) of syndromes, syndrome factors for the clinical syndrome has better coverage, could be better standardized and uniform clinical syndrome.(3) The basic method of treatment and drug research in the15kinds of treatment, in addition to the more common in relieve liver qi stagnation and heat method, of which there are nine kinds of treatment method includes anshen and dingzhi. Can be seen that the heart has played an important role in the occurrence and development of anxiety disorders, Based on the comprehensive analysis, synthesis and judgment of the disease, to formulate a comprehensive treatment approach. Chinese medicine treatment of anxiety disorders, mainly in the sedative, ventilation, antipyretic, and accompanied by the product of the nourish qi and yin, add blood.2. Clinical research: Anxiety patients, more often than not one syndrome, but a variety of syndromes of the merger appear, And syndrome elements can be transformed into each other, showed symptoms of multiple systems, and in symptom clusters in a variety of TCM Syndrome, the symptoms varied. Showing the properties of the deficiency mixed with the disease. Syndrome Elements "Qi stagnation" and "Qi deficiency " is closely related with HAMA score, the results show a positive correlation. That the higher score the syndrome factors are, the more serious the syndrome factors are, the higher the HAMA score is, the more serious the anxiety is.