Open Versus Minimally Invasive Transforaminal Lumbar Interbody Fusion For Lumbar Degenerative Disease:a Meta-analysis

Background:Minimally invasive transforaminal lumbar interbody fusion can be performed through a separate incision using a tubular retractor. Compared with open TLIF. MIS TLIF have smaller surgical field, and reduce surrounding tissue injury, accelerating overall recovery.Objective:To compare the surgical outcome and investigate the clinical value between minimally invasive and open transforaminal lumbar interbody fusion in treatment of lumbar degenerative disease.Methods:According to Cochrane systematic review. Cochrane library, PubMed, Embase, SCI, CNKI, Wanfang Data and Chinese Biomedical Database were searched for controlled trial comparing MIS TLIF and open TLIF in treatment of lumbar degenerative disease. Furthermore, we also searched manually relevant references and four main Chinese orthopedics journals. Methodology quality of the trial was critically assessed and relative data were extracted. Statistical software Revman5.1was used for data-analysis.Results and Conclusion:Three randomized controlled trails and Four case control studies involving856cases were included. The results of meta-analysis showed that no statistically significant differences in the surgical time, complications and fusion rate between MIS TLIF and open TLIF. MIS TLIF was superior to open TLIF in intraoperative blood loss and the time out of bed after operation. Open TLIF was superior to MIS TLIF in Radiation exposure time. MIS TLIF is an ideal surgery to treat lumbar degenerative disease.