| Obesity is a worldwide ubiquitous social problem, especially in economically developed areas. According to the WHO’s definition, the BMI (Body Mass Index) value of obesity is30kg/m. Obesity is a disease of excessive nutrients, not only affecting the appearance, but also leading to many serious complications of the body’s systems, is an important factor which harms the bodies’ health. Obesity is closely related to many other diseases, such as Diabetes, hypertension, hyperlipemia, cardiovascular and cerebrovascular diseases, low ventilation syndrome, sleep apnea syndrome, cholelithiasis, fatty liver, arthritis, gout, infertility, cancer. Related researches showed that the mortality increases as the increase of weight.Obesity is a kind of metabolic disease, which is caused by excessive foods, less exercises and congenital defects. According to Chinese medicine, its reason is the disorder of zang-fu’s functions (spleen and stomach disorders), which blocks the transmitting of body fluid, forming phlegmatic hygrosis gathering in the body, and leads to obesity. So phlegmatic hygrosis is an important cause and interpretation for obesity.This topic studied obesity literatures and made a statistic operation of65prescriptions about obesity. The results showed that most prescriptions about obesity and drugs have the functions of clearing damp and inducing diuresis. According to the results of literatures, the author think that the main pathogenesis of obesity is the disorder of spleen and stomach leading to phlegmatic hygrosis. At the same time, the spleen and stomach disorders is the main reason in the whole process of obesity at different stages, and other organs’disorders are the complementary reasons. The essential pathogenesis of obesity is the standard is asthenia in origin and asthenia in superficiality, and the main viscera are spleen and stomach disease, with other organs included. The main treatment based on syndrome differentiation of obesity is based on treating the phlegmatic hygrosis caused by disorder of spleen and stomach, including promoting blood circulation to remove blood stasis and promoting the circulation of qi, Qi, which is important to the clinical treatment based on syndrome differentiation of obesity.Based on the correlation between obesity and disorders of spleen and stomach and the correlation between melatonin and brown cells, according to the Chinese medicine theory, the author points out the treating method of obesity, and Chinese traditional medicines are mainly used to strengthen the spleen and reduce phlegm, with adjusting other zang-fu and pathogenic factors, at the same time, the drug should be enriched with melatonin, which not only offers a new way to the prevention and treatment of obesity, but also provides a theoretical basis and a new way for the clinical TCM treatment of obesity.1.ObjectiveBased on the systematic arrangements and statistical analysis of literatures about past dynasties doctors regarding obesity etiology, pathogenesis and essential medicines, the author hope to reveal the correlation between obesity pathogenesis, treatment methods and viscera, yin and Yang, Qi blood and body fluid from the angle of philology.According to the research results of modern medicine about obesity and melatonin-brown cells correlation, the author explore the relation between obesity and melatonin-brown cells.According to the comparative studies of traditional Chinese medicine and Western Medicine’s theories about obesity, clarify the new way for obesity of strengthening the spleen and reducing phlegm and replenishing melatonin. The author hope that the study can offer a overall theoretical guide of treating obesity.2methods:2.1Bibliography(1)Collecting collating and analying related records of obesity in ancient literature.(2) Studying the theoretical basis of obesity and disorder of stomach and spleen.(3) Studying the key pathogenesis and phase symptom complex factors of obesity.(4) Studying the mechanism,law and treatment between disorder of stomach and spleen and obesity.(5) Studying the correlation of obesity and melatonin-the brown fat and to explore the role in guiding the treatment of obesity.2.2Statistical methodsUsing statistical methods to study prescription effect,category, efficacy and Meridian and melatonin content of prescription in the literature to treat obesity.3Results:3.1The literature study(1)The most critical pathogenesis of obesity is disorder of stomach and spleen.It always accompanied by qi deficiency, blood stasis, phlegm and other risk factors.The nature is vacuity and based on stomach and spleen and acompanied with other organs.(2) The etiology and pathogenesis and disease location of obesity is corresponded to organs.(3) There are closely related of diseased parts,etiology and pathogenesis, syndrome differentiation between obesity and disorder of stomach and spleen.(4) The melatonin-the brown fat reducted with the increase of age. (5)There are full of melatonin in spleen potion drugs.3.2Statistical research resultsThe statistics shows that in the all65prescriptions to treat obesity,the most is removing dampnessin prescription.it is26.There are14replenishing prescription.6expectorant prescriptions,6consume prescriptions and5diarrhea prescriptions. Effectiveness classification:The most medicine is phlegm dampness medicine which is40.Then is tonic medicine which is25.There are also14antipyretic medicine,12relieving medicine,10activating blood medicine and9diarrhea medicine.It indicated that the dampness, expectorant, tonic (qi-based) medicine and prescription is the most commonly to use to treat the disease of obesity and the critical pathogenesis of disorder of stomach and spleen is dampness.It related to the melatonin content of the130herbs.It showed the relactive of melatonin content and spleen dampness drugs, most of which contains high content of melatonin content. The main pathogenesis of obesity is dampness caused by deficency of stomach and spleen qi which can explain the close relate between melatonin and disorder of stomach and spleen.4Conclusion:4.1The key pathogenesis of obesity is disorder of stomach and spleen.(1) In this study,it shows that the key pathogenesis of obesity is disorder of stomach and spleen after literature study, logic analysis and statistical methods.(2) Phlegm, qi stagnation and blood stasis is also the pathogenic factors.(3) The nature of the pathogenesis of obesity is vacuity. Mainly to the spleen and stomach and also organs of other organs.4.2There are correction between obesity risk factors and melatonin-brown fat cells(1) brown fat cells can increase the non-trembling heat, contribute to the burning of white fat which can keep weight loss.(2) Melatonin can activate brown fat cells via malatonin receptors of brown fat cells which burn fat and keeps weight loss.4.3Prevention of obesity is mainly from the Spleen, the conditioning of other organs, removal and folders pathogenic factors, rich in melatonin Chinese medicine.4.3Dampness-remove drugs should be used to the prevention and treatment of obesity.Remove other pathogenic factors is always important vis Chinese medicine full of melatonin. |
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