| Objective:To investigate shuwei soup functional dyspepsia disharmony of liver and permit patients clinical efficacy and part of the role mechanism.Methods:Select Hunan University of Traditional Chinese Medicine, First Affiliated Hospital gastroenterology clinic, inpatient department, endoscopy room, as well as social recruitment line with functional dyspepsia disharmony of liver and Diagnostic Standards of volunteers40cases. The principles of randomized controlled divided into two groups, the treatment group and the control group, respectively to give Shu stomach soup and Weisu particles,4weeks of treatment, the clinical symptoms and signs of change before and after treatment, and detected in the serum of5-HT SS content changes.Results:1.Treatment group and control group after treatment, the total efficiency of90%,65%, and the difference was statistically significant (P<0.05), table Mingshu stomach soup disharmony of liver and permit patients clinical efficacy in the treatment of FD better than control group.2.Treatment and control groups before treatment, symptom score comparison, the difference was not statistically significant (P>0.05), comparable; After treatment, symptom score, compared with before treatment, the difference was statistically significant (P<0.01) description of treatment in the two groups can to improve FD hepatogastric not clinical symptoms and permit patients; while after treatment between the two groups was statistically significant (P<0.05), the Table the Ming Shu stomach soup in improving FD hepatogastric not and permit patients symptoms better than control group..3.Two groups on the symptoms have improved significantly (P<0.05), but the treatment group of abdominal distention, abdominal pain, hi heave a deep sigh, poor appetite and indigestion, vomiting efficacy superior to the control group (P<0.05).4.The two groups after treatment than before treatment,5-HT were lower, and the difference was statistically significant (P<0.05), showed that the treatment group and the control group can improve the blood level of5-HT. Treatment group compared to the control group, the difference was statistically significant (P<0.05), to said the Ming Shu stomach soup can reduce serum5-HT content, and better than the control group.5. Treatment in both groups, SS than before treatment were lower, and the difference was statistically significant (P<0.05), showed that the treatment and control groups can improve the level of blood in SS. Treatment group compared to the control group, the difference was statistically significant (P<0.05), to said the Ming Shu stomach soup can reduce serum SS content, and better than the control group.Conclusion:Shu stomach soup treatment of functional dyspepsia disharmony of liver and certificate patients total effective rate of90%, Chinese medicine can significantly improve the clinical symptoms, particularly abdominal distention, abdominal pain, hi heave a deep sigh, poor appetite and indigestion, vomiting efficacy superior to the control group, to reduce the content of serum of patients with5-HT, SS. Comfortable stomach Decoction of functional dyspepsia hepatogastric not and certificates may be lower serum5-HT, SS content, thus improving their clinical symptoms. |
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