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Using STI Appraisal Coronary Disease Patient Left Ventricle Twisting Motion

Posted on:2013-04-26Degree:MasterType:Thesis
Country:ChinaCandidate:Z N LiuFull Text:PDF
GTID:2234330395966232Subject:Medical imaging and nuclear medicine
Abstract/Summary:PDF Full Text Request
ObjectiveThis research application two-dimensional spot tracing image formationtechnology (STI) unites when the conventional echocardiogram quantitativeanalysis coronary disease patient coronary artery different pathological changedegree left ventricle twisting motion, when discussion coronary artery differentpathological change degree left ventricle twisting motion change and with leftroom function relations.MethodsGathering103example coronary disease patient who (CAG) confirmedafter the coronarography through uses Simpson ’ the s biplane method in theapex cordis four cavity view section survey left ventricle to shoot themenstruation number (left ventricular ejection fraction, LVEF), the left ventriclecontraction end volume (left ventricular end systolic volume, LVESV) and the leftventricle diastole end volume (left ventricular end diastolic volume, LVEDV),through gathers the left room minor axis moral nature and the apex cordishorizontal section two-dimensional gray scale dynamic image, the applicationtwo-dimensional strain software obtains the revolving curve to achieve thesurvey heart point degrees rotation peak value, to reach the peak time as wellas the left room minor axis base base degrees rotation peak value, reaches thepeak time, and calculatesThe left ventricle whole reverse angle peak value,reaches the peak time.And chooses the health physically healthy30examplesto carry on the above inspection and image gathering same time as the controlgroup. Carries on the Gensini integral appraisal to the selected patient, will be selected according to the computation obtained result the patient to divide intothree groups: The integral is bigger than was equal to that5points, are smallerthan25divide into the mild pathological change group, the integral are biggerthan were equal to25points, are smaller than60divide into the moderatepathological change group, the integral are bigger than were equal to60divideinto the specific weight pathological change group.Results1、Conventional supersonic beacon comparison(1)The coronary artery mild pathological change group and the controlgroup left ventricle shoots the menstruation number (left ventricular ejectionfraction, LVEF), the left ventricle contraction end volume (left ventricular endsystolic volume, LVESV), the left ventricle diastole end volume (left ventricularend diastolic volume, LVEDV) compares, difference non-statistics significance(P>0.05).(2)The coronary artery moderate pathological change group comparesthe control group, the mild pathological change group left ventricle to shoot themenstruation number (left ventricular ejection fraction, LVEF) decreases, the leftventricle contraction end volume (left ventricular end systolic volume, LVESV),the left ventricle diastole end volume (left ventricular end diastolic volume,LVEDV) increases, the difference has statistics significance (P<0.05).(3)The coronary artery specific weight pathological change groupcompares the control group, the mild pathological change group, the moderatepathological change group left ventricle to shoot the menstruation number (leftventricular ejection fraction, LVEF) decreases obviously, the left ventriclecontraction end volume (left ventricular end systolic volume, LVESV), the leftventricle diastole end volume (left ventricular end diastolic volume, LVEDV)increases obviously, the difference has the remarkable statistics significance(P<0.05). 2、Coronary artery different pathological change degree left room revolvingand reverse parameter comparison(1)The coronary artery mild pathological change group and the controlgroup quite left room minor axis (base base and heart point) the degreesrotation and the left room whole reverse angle peak value slightly decreases,and reaches the peak time to retard slightly, the difference does not havestatistics significance (P>0.05).(2)The coronary artery moderate pathological change group and thecontrol group, the mild pathological change group quite left room minor axis(base base and heart point) the degrees rotation and the left room wholereverse angle peak value decreases, and reaches the peak time delay, thedifference has statistics significance (P<0.05).(3)The coronary artery specific weight pathological change group and thecontrol group, the mild pathological change group, the moderate pathologicalchange group quite left room minor axis (base base and heart point) thedegrees rotation and the left room whole reverse angle peak value decreasesobviously, and reaches the peak time to retard obviously, the difference hasstatistics significance (P<0.05).3、During various targets relevant analysis(1)In the coronary artery mild pathological change group, the left roomwhole reverse angle peak value and the left ventricle diastole end volume (leftventricular end diastolic volume, LVEDV), the left ventricle contraction endvolume (left ventricular end systolic volume, LVESV) assumes the inversecorrelation, r=-0.87, P=0.002and r=-0.83, P=0.003; Shoots the menstruationnumber with the left ventricle (left ventricular ejection fraction, LVEF) presents isrelated r=0.80, P=0.012.(2)In the coronary artery moderate pathological change group, the leftroom whole reverse angle peak value and the left ventricle diastole end volume(left ventricular end diastolic volume, LVEDV), the left ventricle contraction end volume (left ventricular end systolic volume, LVESV) assumes the inversecorrelation, r=-0.85, P=0.002and r=-0.82, P=0.004; Shoots the menstruationnumber with the left ventricle (left ventricular ejection fraction, LVEF) presents isrelated r=0.72, P=0.022.(3)In the coronary artery specific weight pathological change group, theleft room whole reverse angle peak value and the left ventricle diastole endvolume (left ventricular end diastolic volume, LVEDV), the left ventriclecontraction end volume (left ventricular end systolic volume, LVESV) assumesthe inverse correlation, r=-0.76, P=0.018and r=-0.73, P=0.022; With shoots themenstruation number with the left ventricle (left ventricular ejection fraction,LVEF) presents is related r=0.66, P=0.035.Conclusions1、Coronary disease patient left room twisting motion angle parametercompares the control group to decrease, the time parameter compares thecontrol group to retard.2、Coronary disease coronary artery different pathological change degreepatient along with the pathological change degree’s aggravation, the twistingmotion angle parameter decreases gradually, the time parameter retardsgradually.3、Coronary disease patient reverses the angle parameter and the left roomfunction has the good relevance.4、The left room twisting motion parameter target appraises the left roomfunction the method to be able to reflect the coronary disease patient left roomthe contraction function.
Keywords/Search Tags:Speckle trackong imaging, Coronary heart disease, Ventricular function, left
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