The Study Of The Curative Effect On The Cognitive-behavioral Therapy Combined With Antidepressant Drugs In The Treatment Of Depression With Somatic Symptoms

Objective: According to incomplete statistics,69%of depressedpatients with somatization symptoms, If the somatization symptoms cannot get effective relief, would reduce the clinical cure rate ofantidepressant treatment. Duloxetine is currently treating depression bodysymptom first drug, although duloxetine is superior to the other in termsof treatment and effective antidepressant drugs, but the cure rate is stillnot satisfactory.Therefore, this topic mainly according to the pathogenesisof depression somatization symptoms, discusses application of cognitivebehavior therapy in combination with antidepressant (duloxetine)treatment of depression somatization symptoms, work time, clinical effect,compare average dose use drugs, side effects and predict prognosis ofpatients.Method: This study selected conforms to the diagnosis ofdepression with somatic symptoms in60patients, are all in May2011toMay2012visits during the first hospital of jilin university psychiatristoutpatient treatment of patients.60patients were divided into researchgroup and the control group,30cases each, the team with duloxetinehydrochloride and cognitive behavior therapy combined treatment,control group treated with duloxetine hydrochloride alone. In before andafter treatment for2weeks,4weeks,8weeks and12over the weekendby the self-assessment lists of symptom various factors (SCL-90) and Hamilton depression scale (HAMD)12weekends of points rate to assesscurative effect, adverse reaction symptom scale (Tess) to evaluate theadverse drug reactions. Using SPSS15.0software to complete statisticaltreatment, P <0.05for the difference was statistically significant.Result: Treatment2weeks and4weeks,8weeks,12weekend, theteam of somatization, depression, anxiety and other factor pointscomparing with control group there were significant differences (P <0.05), the team’s significant efficiency efficient is better than controlgroup, all have significant difference (P <0.05). These two groups ofadverse reactions, no statistical significance (P>0.05).Conclusion:1.Application of cognitive behavior therapy in combination withduloxetine treatment compared with drug therapy alone, shortened theworking time.2. Joint application of both treatment and improve the treatmentefficiency and effectiveness, improve the clinical curative effect.3. Cognitive behavioral therapy had no effect on drug side effects,but can reduce the daily dose of drugs, reducing patient pain medication,at the same time reduce the economic burden.4. Cognitive behavioral therapy can improve the patientsmedication compliance, cooperate treatment has certain promoting effecton the patients. This study on patients with long-term follow-up, butimprove the patients compliance, has a positive promoting effect onprognosis and prevention of recurrence.