A Study On The Pathogenic Agents And Clinical Characteristics In Community-acquired Pneumonia Of Primary Hospital

Objective To investigate the clinic symptoms, epidemiological features,etiology distributions and drug resistance of community-acquiredpneumonia（CAP）patients in primary hospitals, and provide a guidancefor diagnose and treatment, as well as the use of anti-infective agent forCAP patients in these hospitals.Method A retrospective analysis was conducted on the hospitalizedpatients with CAP from October2009to October2011in in YingdePeople Hospital from May2008to May2012.Result The Male/Female ratio of524CAP patients was3:1,83.02%(435/524) of patients aged older than60;94.08%,77.10%and83.59%of patients appeared cough, expectoration and fever;81.52%(375cases) of patients had respiratory underlying diseases.72.61%(334cases)of them are chronic obstructive of pulmonary disease (COPD); Detectionrate of sputum and blood culture was36.83%(186cases), Mycoplasmapneumoniae positive rate was24.58%(53/236); the positive rate ofsputum culture was26.15%(137/524), Gram positive bacteria was accounted for22.56%, while77.44%for Gram negative bacteria, thecommon pathogen in sequence were Haemophilus influenzae (33cases,21.71%), Klebsiella pneumoniae (28cases,18.42%), Streptococcuspneumoniae (21cases,13.82%), Haemophilus parainfluenzae (15cases,10.42%), escherichia coli (9cases,6.25%). The fungal were seen in11cases（7.64%）, they were Candida albicans (7cases) and Aspergillus (4cases).17patients (8.81%,17/186) were mixed infected by two or morethan two pathogens, the most common infection was Mycoplasmapneumoniae combined Haemophilus influenzae (6cases,1.14%). CAPpatients with sputum culture-positive and-negative，sputum bacterialculture Gram-positive and Gram-negative bacteria were affected by therespiratory underlying diseases (P<0.05).Conclusion CAP patients in Yingde district were majority of elders,most of them combined with COPD, the most common symptoms werecough, expectoration and fever; Mycoplasma pneumoniae was the mostcommon pathogen, the Gram negative bacteria took the first place inbacteria culture, the other common pathogen were Haemophilusinfluenzae, Klebsiella pneumoniae and Streptococcus pneumoniae; therespiratory underlying diseases could affect the etiology distributions insputum. Further studies should be taken to explore the differencesbetween CAP patients in primary and central cities hospitals.