Application Vacuum Sealing Drainage(VSD)on Damage And Defect Of Extensive Skin,soft Tissue And Deep Tissue

Objective：To investigate the effects of vacuum sealing drainage(VSD) ondamege and defect of extensive skin,soft tissue and deep tissue repairing.Methods：24cases of patients in our Hospital with extensive skin,softtissue and deep tissue defect were involved from March2011to December2011.Two methods, combination of VSD and auto skin grafting (group A) orcombination of acellular xenograft dermal matrix(DR) and auto skin grafting(group B) were useded to repair damege and defect of extensive skin,soft tissueand deep tissue.Body temperature, white blood cell count were recorded during1,3,6,9days after debridement in two groups.The rate of negative-invertedbacteria cultures and numbers of dressing were recorded during9dads afterdebridement.The time point the wound became clean, numbers of operation andthe time of wownd healing were recorded also well.Results: There were no significant difference (P>0.05) on bodytemperature, white blood cell between two groups.1,3,6,9days after debridement. The rate of negative-inverted bacteria cultures and numbers ofdressing during9days after debridement in group A were72.7%(8/11),1.5times.the time point the wound became clean, numbers of operation and the timeof wownd healing in group A were13.2days,1.7times and33.3daysrespectively; the rate of negative-inverted bacteria cultures and numbers ofdressing during9dads after debridement in group B were20.0%(2/10),4.1times.the time point the wound became clean, numbers of operation and the timeof wownd healing in group B were19.9days,2.8times and42.1daysrespectively. Difference in group A and group B were statistically significant (P<0.05), compare with the rate of negative-inverted bacteria cultures, the timepoint the wound became clean, numbers of operation and the time of wowndhealing.Conclusions: Repairing of damge and defect of extensive skin,soft tissue anddeep tissue was promoted with VSD, the curative effect of combination ofVSD and auto skin grafting (group A) was superior to combination ofxenograft dermal matrix (DR) and auto skin grafting.