| Object: The object is to evaluate left ventricular function in patients withleft ventricular abnormal filling pattern by using strain rate imaging（SRI）, andto investigate the clinical value of the SRI in the evaluation of left ventricularfunction.Method: The62cases of abnormal left ventricular diastolic function aredivided into3groups according to different filling patterns of the left ventricle,which are the relaxation drop group, pseudonormal filling group and restrictivefilling group. The first group contains23cases, the second group contains19cases and the last group contains20cases. There are30male cases and32female cases in the total62cases, with the average age of57.30±8.84years.Normal group contains21cases, in which11are male and10are female, withthe average age of53.00±2.37years. After detailed history taking,cardiovascular and respiratory diseases are excluded by physical examination,electrocardiogram, and echocardiography. All the objects of study are done withtwo-dimensional ultrasound echocardiography, three-dimensional ultrasoundechocardiography and strain rate imaging technique. The peak systolic strain rate (SSR), early diastolic peak strain rate (ESR), and late diastolic peak strainrate (ASR) of each wall of the left ventricule were recorded, then analyzed andcompared among groups.Result: The ESR of different filling pattern are statistically different (P<0.05), and the ESR gradually decreases with the development of impaired leftventricular diastolic function in each group. There is no significant difference ofthe ASR between relaxation drop group and pseudonormal filling group (P>0.05)，and there is significant difference among other groups (P<0.05). ASR ofrelaxation drop group and the pseudonormal filling group is higher than thenormal group, and ASR of restrictive filling group is lower than normalgroup.Except the normal group and relaxation drop group, the SSR difference isstatistically significant in the remainder (P <0.05), which of pseudonormalfilling group is higher than the normal group, and of the restrictive fillingdisorder group is lower than the normal group.Conclusion: Objective and quantitative evaluating for the changes of leftventricular myocardial function in patients with abnormal filling patternsthrough the application of SRI, provides quantitative indicators for clinicalevaluation of the damage extent of left ventricular diastolic function. |
