Phlegm Act Joint Metformin Treatment Of Kidney Phlegm Type PCOS With IR Clinical Observation

Objective:In this study, the treatment of kidney phlegm polycystic ovary syndrome with insulin resistance in clinical research for Integrative Medicine, Observation phlegm metformin kidney phlegm and polycystic ovary syndrome with the clinical efficacy of insulin resistance, contrast to pure Western medicine before and after treatment in patients with menstruation, the BBT biphasic changes, acne, changes in ovarian volume and serum follicle stimulating hormone (FSH), luteinizing hormone (LH), testosterone (T), fasting insulin (FINS), fasting plasma glucose (FPG) changes, and to explore the possible mechanism of phlegm in the treatment of polycystic ovary syndrome with insulin resistance, In order to provide the scientific basis of phlegm in the clinical treatment of polycystic ovary syndrome.Methods:Select outpatient and inpatient that treated in Shiyan Chinese Medicine Hospital Gynecological which Affiliated with the Hubei University of Chinese Medicine Since March2010to December2011. A total of60cases of patients with polycystic ovary syndrome Which Met the inclusion criteria were randomly divided into Integrative Medicine Group and Purely Western control group. Integrative Medicine Group treated with Phlegm combined with metformin, Western control group simply metformin oral treatment. The treatment lasted three months, Observed Before and after treatment of clinical symptoms, signs and other changes (menstruation, body weight, BBT, etc.), Fasting venous blood collected before treatment and after3months of treatment, Serum follicle stimulating hormone (FSH), luteinizing hormone (LH), testosterone (T) fasting plasma glucose (FPG), fasting insulin (FINS) change, observed changes in the B ultrasonic measurement of ovarian volume to determine its clinical efficacy.Results:Clinical effects by treatment of the treatment group and control group, the difference of the total effective rate was statistically significant (P<0.05), the clinical effects of the treatment group better than the control group. Chinese medicine symptom efficacy compared, The difference was significant (P<0.05), Of TCM Hou efficacy of the treatment group than the control group. The number of cases in Improve Menstrual, Treatment group is more than the control group, BBT biphasic cases the number of treatment group, significantly more than the control group; Difference between the two groups were significant (P<0.05). After treatment, treatment group and control group were lower in LH, LH/FSH, T, There are significant differences (P<0.05), Compared with the control group, there are significant differences in LH, LH/FSH and T significantly reduced in Treatment group (P<0.05). After treatment, FINS of the treatment group and control group were significantly lower, and the ISI were significantly higher, there are significant differences (P<0.05). Treatment group and control group, FPG change significantly, no significant difference (P>0.05); the treatment group and control group of FINS, the ISI there are significant differences (P<0.05) FPG no significant difference (P>0.05). The two groups of patients with ovarian volume than before treatment reduced, the difference was significant, control group (P<0.05), Treatment group (P<0.01); Treatment group than the control group improved significantly, Have a very significant difference (P<0.01). After the treatment, treatment group compared with the control group, no significant difference in the number of acne patients (P>0.05). Decreases in the two groups of BMI than those before treatment, After the treatment, the difference was significant (P<0.05); The treatment group, BMI, compared with the control group, no significant difference (P>0.05).Conclusion:Phlegm method combined with metformin can effectively improve the clinical symptoms and signs of PCOS, can be significantly reduced in patients with LH, LH/FSH, T, FINS, increased the ISI, Chinese and Western medicine therapy of PCOS have good modulating effect.