| Objective:Percutaneous coronary intervention is essential for ST elevated myocardial infarction (STEMI) patients in subacute phase with ischemia symptoms. To investigate the possible effects refflected by coronary microvascular resistance index after PCI for patients with STEMI.Methods:1. Objects and settingsA total of46patients with SETMI in subacute phase were enrolled in the study from February2011to April2012. All patients were hemodynamic stability, had delayed PCI therapeutic indications. All patients were taken coronary angiography, and after angiography all of the subjects operation decision according to the doctors experience support: direct stenting or conventional stenting. Use the coronary pressuse wire to measure IMR after PCI, a cut-off value of32U could differentiate and the patients were divided into2groups:normal microcirculation function (groupA, n=31), microcirculation dysfunction (group B, n=15)Results:1. There were no significant differences of clinical characteristics between the two groups, such as age, gender composition, history of hypertension, blood cholesterol, smoking; there were also no significant differences with the number of implanted stent,stent diameter and size between the two groups.2. We found a positive correlation between the type of PCI mode and the levels of IMR after PCI(p<0.01).3. We found a positive correlation between the culprit on plaque and the levels of IMR after PCI(p<0.05)Conclusions:1. The results of the present study suggested that uncomplicated direct stenting had lower rate of microvascular injury which was evaluated by IMR than conventional stenting, and direct stenting may decrease the injury in patients undergoning PCI with STEMI in subacute phase.2. The conventional stenting could induce the injury in patients undergoning PCI with STEMI in subacute phase3. The more interventional operation on culprit artery plaque, the coronary microcirculation function injury gets more serious. |
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