The Comparison The Therapeutic Results Of Between Pre-dilaion Renal Artery Stenting And Direct Renal Artery Stenting

Objectives: To evaluate the different therapeutic results of pre-dilation renal artery stenting and direct renal artery stenting, investigate the possible mechanism.Materials and methods Analyze the patients with hypertension caused by renal artery obstructive disease in our hospital from December, 2001 to December, 2004, who successfully underwent pre-dilation renal artery stenting (group A) and direct renal artery stenting (group B). Each group were 15 patients. Samples of peripheral serum in both groups were obtained to determine the serum interleukin 6 (IL-6) and C-reactive protein (CRP) levels before and 6h, 48h, and 7d after operation. Record patient's X-ray exposure time, operation time, contrast media volume in operation. Record blood pressure and serum creatinine (Cr) before and after operation. Have a follow-up investigation of blood pressure, Cr and color doppler sonography (CDS) in 1,3,6,9,15month. The observed figures were statistically analyzed by T-test.Results (1)The levels of IL-6 6h after operation and CRP 48h after operation in the two groups were significant higher than those before the operation(P<0.001) (IL-6: 12.26±3.29pg/ml vs 5.43±2.14 pg/ml in Group A and 9.33 ±2.42pg/ml vs 5.07+1.87pg/ml in Group B; CRP: 15.03±3.15mg/l vs 6.29± 1.89mg/l in Group A and 11.67 ± 2.34mg/l vs 6.46± 1.47mg/l in Group B). There was no difference in IL-6 and CRP before and 7d after operation (P>0.05). (2)The peak values of IL-6 and...