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The Study About The Effect Of Tiao He Yin On Endome Trial Of Er(+), Pr (+)and Her-2(-) Breast Cancer Patients Who Take Tamoxifen

Posted on:2013-02-05Degree:MasterType:Thesis
Country:ChinaCandidate:J C WangFull Text:PDF
GTID:2234330374983945Subject:Chinese medical science
Abstract/Summary:PDF Full Text Request
objective:discussion oneself make of traditional Chinese medicine tiao he yin treatment menopause Qian by surgery and chemotherapy radiation treatment breast cancer oral endocrine drug three benzene oxygen amine, observation three benzene oxygen a mine on endometrium of effect and female hormone fell led to of TCM clinical symptoms of changes, and oral tiao he yin is reduced three benzene oxygen amine led to of endometrium incr eased thick, improve female hormone reduced by led to of TCM clinical symptoms of changes. Improve oral tamoxifen breast ca ncer quality of life, provides data for clinical research.Method:select January2011-2011years December during, in since Heilongjiang Chinese medicine University subsidiary II hospital, Harbin city hospital of traditional Chinese medicine oncology outpatient and ward of meet into and excluded standar d of breast cancer patients60cases, select of general situation (name, and age, and hospital number and hospital time, and ho spital,,) clinical symptoms signs, and hospital days, and TCM cl inical symptoms, and using have Chinese medicine situation, and secondary check results relative full of patients. Randomly divi ded into60cases patients of the control group, respectively (or al tamoxifen he only), the treatment group (oral tamoxifen also oral traditional Chinese medicine tiao he yin separately)30cas es respectively, and statistical analysis of the information collec t.The result:1Comparison treatment of symptom score before an d afterl) Two groups of treatment before and after with no signi ficant differences (P>0.05) the treatment group and the control Group score is can comparable.2) Control group treatment of sy mptoms before the is score divided intol4.97±1.67Treatment of symptoms after the score is divided int16.97±1.75, it than befo re treatment had significant differences.(P<0.05)3) Treatment of symptoms before treatment product is divided into14.53±1.96T reatment of symptoms after the score is divided into8.70±1.64, i t than before treatment had significant differences (P<0.01)..4) Treatment of the latter two groups score comparisontreatment grou p score8.70±1.64Treatment of symptoms after the score is divid ed into16.97±1.75Statistical analysis of significant differences(P <0.01)2Before treatment and after treatment Comparison of en dometrial1) Two groups before and after the treatment of endo metrial no significant differences(P>0.05) treatment group and control group of endometrial There is no comparison2) Control g roup before the treatment of endometrialThickness4.20+1.50Aftert reatmentofendometrialThickness is8.70±2.87Treatment than before there is a significant statistical difference(P<0.01)3) Treatment groupEndometrial thickness before treatmentis4.13±1.55After tre atment of endometriosis5.83±2.32before treatment had significan t differences(P<0.01)4) After the treatment Two groups of Comp arison of endometrial treatment5.83±2.32Control group8.70±2.87Statistical analysis of significant differences (P<0.01)Conclusion:the statistical analysis of tiao he yin for Premenop ausal Breast cancer after surgery radiation treatment and chemother apy of oral tamoxifen cause endometrium thickening And clinica1symptom score changes as there is a clear improvement, mechan ism of action could be, reducing it xenoestrogen effect of tamoxifen, tiao he yin for nourishingtheliverandkidney, improve deficiency-fire, strengthening thespleenand onifying the kidney and conditioning The liver. Conditioning the chong and ren pulse. Stress rib Swelling, e motional depression, quick irritability, anorexia less food, tiredn ess and fatigue, sallow complexion, soreness of the waist and t he knees, palpitation and insomnia night insomnia and forgetful cli nical symptoms improved significantly.
Keywords/Search Tags:ER+, PR+in Premenopausal Breast cancer, after chemotherapy and radiation treatment, retrospective studies, clinical features of traditional Chinese medical science
PDF Full Text Request
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