In Urine Test-SH For Cervical Cancer And Precancerous Lesions Of Significance

Objective:Discuss a new screening method of cervical cancer and cervical precancerous lesions--cervical cancer fast self-check kit (FST-SH) molecules urine test.Evaluate this new method in clinical screening cervical intraepithelial neoplasia and cerical cancer clinical significance.Objects and methods:Analysis of327cases collected from October2010to March2012,to Qilu Hospital of Shandong University gynecological clinic and medical examination women. Including81cases diagnosed by clinical gynecological examination, the TCT and pathologic biopsy in patients with cervical precancerous lesions,42cases of clinical gynecological examination, the TCT and pathologic biopsy diagnosed as cervical cancer,204cases of patients with other gynecological diseases, but clinical gynecological examination, TCT and pathologic biopsy in patients with normal cervical (hereinafter referred to as cervical benign group). On the above327patients of group, divided into benign cervical group,CINI group, CINII group, CIN Ⅲ Group and cervical cancer group.Record the patient’s age, health status, test results of the TCT (TCT), histopathological examination findings, the patients were used respectively to cervical cancer fast self-check kit (FST-SH) testing its sulfhydry in the urine and patients already TCT (TCT) to check the results for comparison. Check data applications Microsoft excel2003the establishment of a database, check the correct import SPSS software for statistical analysis. Results:Use of cervical cancer fast self-check kit (FST-SH) respectively CINI group, CINII test group, CIN III group, cervical cancer group and cervical benign groups of patients in the urine sulphur, get of positie were72.7%,77.4%,96.9%,95.2%,18.6%, and the differences between the groups was statistically significant (P<0.05), so will the CINI group and more than CINII combination and CINII or group, will CIN III group and cervical cancer combination and CIN III group for frequency, with FST-SH method to detect the above two of positive group were75.7%,95.9%. Use of liquid and thin layer cytology (TCT) test CINI group, CINII group, CIN III group, cervical cancer group, cervical benign group, CINII group and frequency than CIN III group of positive patients receive were83.3%,87.1%,90.6%,92.9%,5.9%,85.6%,91.9%. To compare two screening method of the data differences, including statistical significance of groups for cervical benign group and cervical cancer group, no statistical significance for CINI group, CINII group, CIN III group, CINII group and frequency than CIN III group. With cervical cancer fast self-check kit (FST-SH) screening cervical cancer and cervical cancer lesion before the special degree, the positie predictie alue, negatie predictie alue, positive likelihood ratio, negative likelihood ratio on about index were81.4%,74%,91.7%,4.7,0.15,0.7.Conclution:Cervical cancer fast self-check kit (FST-SH) method of cervical cancer and cervical precancerous lesions has high sensitivity and specific degrees, especially for CIN III and cervical cancer screening were far higher than to CINI and CINII screening test. It is a safe and effective, and to the body without traumatic, low prices and don’t need to be equipment can quickly to obtain the result of cervical cancer and cervical precancerous lesions.