Clinical Effect Of Piribedil Sustained-release Tablets In The Treatment Of Coma Patients

OBJECTS: to observe the clinical effect of Piribedil Sustained-releaseTablets in treatment of coma.METHODS:60patients with coma were randomly divided into twogroups (30cases per group). The control group was treated with routinemedicine according to the primary disease. The treatment group was treatedwith the addition of Piribedil Sustained-release Tablets50mg with nasalfeeding tube on basis of routine treatment，once a day,21days as atherapeutic course in both groups. The degree of coma was evaluated byGlasgow Coma Scale (GCS).RESULTS: the average GCS in both groups were significantlybetter than that before the treatment at different time points， andsignificant difference was observed between the two groups (P<0.05); Theincreased GCS score at different time points in the treatment group weresignificantly better than those in the control group（all P<0.05)；The totaleffective rate in the treatment group was93.3%,and that in the control groupwas70%after21d treatment, there was significantly different between thetwo groups (P<0.05);The GCS score in the treatment group was significantly improved(10d vs5d,14d vs10d, P<0.05).CONCLUSIONS: on basis of routine treatment, the addition ofPiribedil could significantly improve the coma patients，consciousness.