| Objective Through preliminary study for the effective parts of Xiongma soup cure of migraines,find out effective component,as a representative of the effective parts.this research can provides the basis for Xiongma soup cure of migraines in further.Method Adopt thin layer chromatography(TLC)and high performance liquid chromatography(HPLC),these two fingerprint analysis method in order to analysis Xiongma soup fried、point fried and single herb medicine decoction find out that two decoction way for changes in matter,and if fried produce new matter.in the same time,adopt HPLC can also draw each chromatography peak belongs. Adopt Nitroglycerin rats mice and low5-HT migraine model, with serum5-HT and NO variation in content of as the index, through the statistical analysis of the results we can get evaiuation of that Xiongma soup cure of migraine animal models. Compatibility relations of River xiong and Gastrodia elata. Aanalysis Xiongma-soup transitions composition in rats blood.find out composition which absorption into the blood. And these composition belong to which parts. Results There is no new matters in the Xiongma soup fried,but,same content of composition happened obxious change. Effect obvious about Xiongma-soup cure of migraine.Rhizoma Chuanxiong as a gentlement medicine play a major therapeutic effect. Gastrodia elata Blume as official medicine play cure of effect.there is not obvious·difference beteen fried and points fried. Gastrodia elata element and Ferulic acid of phenolic acids;ligustrazine of alkaloids as effective parts of Xiongma-soup certain cure of migraine.Same matters in the bloood need ensure about structure.in order to ensure that belong to which parts.Conclusion:Gastrodia elata element and Ferulic acid of phenolic acids;ligustrazine of alkaloids as effective parts of Xiongma-soup certain cure of migraine. |
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