| Objectives:To explore the prevalence and correlates of impaired fasting glucose (IFG) in population aged20to79in Tianjin, and identify the optimal adiposity measure indices to IFG and new diagnosed type2diabetes mellitus (T2DM) among body mass index (BMI), waist circumference (WC), waist to hip ratio (WHR) and waist to height ratio (WHtR).Methods:A multi-phasic stratified cluster sampling method was adapted and7567sujects aged20to79and having lived for≥5years in Tianjin were investigated. Information on risk factors was collected through face-to-face questionnaire interview, physical examination and laboratory test. IFG and T2DM were diagnosed according to the diagnostic criteria of World Health Organization in1999. Logistic regression analyses were used to estimate the odds ratios (ORs) and95%confidence interval (CIs) of IFG in relation to related factors after adjusting for other potential confounders. The receiver operating characteristic curve (ROC) analysis was used to compare predictive ability of adiposity measure indices for IFG and newdiagnosed T2DM.Results:Of7567participants,536(7.1%) were having IFG, the prevalence of IFG was6.8%in men and7.4%in women respectively (χ2=1.10, P=0.29). Compared with diabetes-and IFG-free subjects, the results of univariate logistic regression shows that old age, the minority ethnic group, obesity, family history of diabetes, hypertension, stressful events, irregular food intake were associated with higher risk for IFG, whereas high average income and more fish, meat, fruit and vegetable intakes were associated with decreased risk for IFG. No relation was found between gender, education, smoke, alcohol drinking and IFG. After adjusting for potential confounders, old age, bigger WHtR, the minority group, irregular food intake, the family history of diabetes, hypertension and stressful events were associated with higher risk of IFG, while high average income and more fish intake were associated with decreased risk of IFG. Four adiposity measure indices including BMI, WC, WHR and WHtR were correlated with IFG. Among the four indices, WHtR≥0.5showed the largest area under the curve (AUC) for identification of IFG (AUC0.662,95%CI:0.638-0.687) and newdiagnosed T2DM (AUC0.725,95%CI:0.693-0.756). WC is also a good indication of IFG and newdiagnosed T2DM in women. The diagnostic sensitivity, specificity and accuracy of WHtR and WC were higher than those of BMI and WHR for IFG and newdiagnosed T2DM.Conclusions:The prevalence of IFG was high in participants. Old age, the minority ethnic group, bigger WHtR, family history of diabetes, hypertension, irregular food intake, and stressful events were associated with increased risk of IFG. High average income and more fish intake were associated with decreased risk of IFG. WHtR may be an effective measure to identify IFG and newdiagnosed T2DM. |
