Study On Esophageal Carcinoma Urgur Traditional Medieine Syndromes And The Change Of T-lymphocyte Subsets And NK Cells Of Patients Before And After Radiotherapy

Objective: To investigate the esophageal carcinoma urgur traditional medieinesyndromes and the change of T cell subsets and NK cell level before and after radiation therapy, and the observation of radiotherapy after those medicine typing inpatients with esophageal cancer with radioactive esophagitis, bone marrow suppression and near future curative effect. Method: To apply Urgur Medicine abnormalhumoral classification standard of before and after radiation treatment in120casesof esophageal carcinoma patients with Urgur medicine typing, and before and afterradiation therapy using flow cytometry in patients with peripheral blood T cell subsets and NK cell level, simultaneously recorded during radiotherapy related clinical features of toxic reactions and curative effect in the near future. Results:（1） before and after radiotherapy, the distribution of esophageal cancer patients can be drawn: abnormal savda（50%）>abnormal belghem（27.5%）>abnormal kan1（15%）>abnormalsapra（7.5%）;after radiotherapy:abnormal savda（76.67%）>abnormal sapra（12.5%）>abnormal kan（7.5%）>abnormal belghem（3.33%）；The proportion of Urgur Traditional Medieine Syndromes has significant difference（P<0.01）;（2） before and after radiotherapy in120cases of patients with esophageal carcinoma T cell subsets and NK celllevel changes: CD₃⁺、CD₄⁺、CD₄⁺\CD₈⁺and NK cell levels were decreased, CD₈⁺before radiotherapy levels are elevated before radiotherapy, and radiation changes before and after treatment was statistically significant（P<0.05）;（3） after radiotherapy,different Urgur traditional medieine syndromes, abnormal savda and abnormal Savda before and after radiotherapy of T cell subsets and NK cell level changes: abnormal savda patients after radiotherapy CD₃⁺、CD₄⁺、CD₄⁺\CD₈⁺and NK cell levels an d before radiotherapy ratio decreased, while CD₈⁺level than before radiotherapy LHigh, and before and after radiotherapy changes were statistically significant（P<0.05）; instead of abnormal Savda in patients before radiotherapy compared with CD₃⁺、CD₄⁺、CD₄⁺\CD₈⁺、CD₈⁺and the ratio of NK cell levels and before radiotherapychanges little, and the changes were not statistically significant,（P<0.05）;（4） afterradiation for abnormal savda of abnormal Savda in patients with esophageal cancerradiotherapy in toxicity and efficacy were compared, found between the two differences, and the differences were statistically significant （P<0.05）. Conclusion: Abnormal Savda is the major Urgur Traditional Medieine Syndromes before and after undergoing radiotherapy; radiotherapy makes abnormal savda humoral form; after radiotherapy abnormal Savda patients with impaired immune function is more and more serious, and the radioactive esophagitis, bone marrow suppression and the recenteffect correlation.