Prediction Of Left Atrial Thrombi In Non-valvular Atrial Fibrillation

Objective: To determine the predictors of thrombosis in1eft atrium(LA)or left amalappendage(LAA)in pailents with nonvalvular atrial fibrillatin.Methods: Three hundredand thirty-nine patients with atrial fibrillation(AF)were included. Thrombus formation inLA/LAA was found in61patients(thrombus group)but absent in the remaining278patients(nonthrombus group). All patients were analyzed by univariate regression andbinary logistie regression to investigate the relationship between the two groups,and thesefactors(such as past history,history of alcohol and tobacco,clinical biochemical andechocardiographic. Results: Univariate analysis revealed that diameter of LA(47.0±6.8)mm vs (39.1±6.7)mm, P=0.000, Left ventricular ejection fraction(LVEF),(53.8±14.8)mm vs (60.6±9.9)mm, P=0.001, Taking aspirin14(23%) vs136(48.9%),P=0.000, Non-paroxysmal atrial fibrillation25(41%) vs63(22.7%), P=0.006. logistieregression found that Diameter of LA, LVEF, Taking aspirin and Non-paroxysmal atrialfibrillation were the significant and independent predictors of LA/LAA thrombosis.Conclusion: Diameter of LA,LVEF, Non-paroxysmal atrial fibrillation are independentrisk factors of thrombosis in patients with nonvalvular atrial fibrillatio. Long-term use ofaspirin to prevent thrombosis anticoagulation is possible.