Clinical Analysis Of13Cases Patients With Mediterranean Anemia

Objective: To analyze the clinical features and prognosis of Mediterranean anemia.Methods: To analyze the clinical data of13cases of thalassemia patients retrospectively.Results: In this group of13patients, aged1to50years old, the average age of17.62years, of which14people under the age of4; male:female is1.17:1; wherein the alphathalassemia beta thalassemia in3cases, in10cases, the ratio is0.3:1; extremely severeanemia in0cases (0.00%), severe anemia in5cases (15.38%), moderate anemia in7cases(53.85%), mild anemia in4cases (30.77%); the serum ferritin as (55.00~180.00) mol/L,for an average of93.15μmol/L, serum iron (Fe) for (11.50~27.00)μmol/L, for an averageof17.69u mol/L, total iron binding capacity for (51.50~69.00), for an average of61.73umol/L; total bilirubin (STB) for (8.20~54.00) mol/L, for an average of24.97u mol/L,conjugated bilirubin (CB) for (1.80~7.70) mol/L, for an average of5.22u mol/L,unconjugated bilirubin (UB) for (6.40~48.600) mol/L, for an average of20.86u mol/LNacl solution for hemolysis; start (3.60~4.40) g/L,4.00g/L average, complete hemolysisfor (2.25~3.50) g/L,2.83g/LNacl solution for an average of. After drugs, blood transfusion,splenectomy and symptomatic treatment,3cases died (15.38%), lost to follow-up in2cases. Conclusion: the Mediterranean anemia as small cell hypochromic, autosomalhereditary hemolytic anemia, serum ferritin, iron staining of bone marrow smear positive,direct bilirubin indirect bilirubin normal, reduced, osmotic fragility, no gender differences.Its distribution region, in South China, see more, North rare, but in recent years in theXinjiang region has a rising trend, clinical misdiagnosis, missed diagnosis.