Analysis Of Correlative Factors Of Causes And Visual Prognosis In Retinal Vein Occlusion

Objective: To investigate factors of the visual prognosis and the causes in patientswith various types of retinal vein occlusion (RVO). Methods: Three hundred andforty-five eyes of three hundred and forty-one patients with various types of RVO wereanalyzed.The age range of patients was16-78years old,(average53.5±12.6).The data ofthe patients were study by SPSS17.0software. Results:(1)Systemic risk factors of RVOwere hypertension (203patients,205eyes,47.2%), atherosclerosis (217patients,218eyes,63.6%), high blood viscosity (86patients,87eyes,25.2%), glaucoma (11patients,12eyes,3.2%), diabetic (24patients,24eyes,7.0%). Different types of RVO in patients hasdifferent systemic risk factors.(2) Local risk factors of RVO were intraocular pressure andaxis oculi.The intraocular pressure with blocking eye compared with the contralateral eyewere lower0.8-5.9mmHg; intraocular pressure day changes in the difference of blockingeyes was on average (4.55±1.47) mmHg, in the contralateral eye was on average (4.30±1.19)mmHg,less than8mmHg. The axis oculi in blocking eyes was on average （22.37±0.51）mm, in the contralateral eye was on average （22.82±0.48）mm.(3)RVO wasclassified into central retinal vein occlusion (CRVO) in150eyes (43.5%) and branchretinal vein occlusion(BRVO) in175eyes (50.7%) and hemi-central veinocclusion(HRVO) in20eyes (5.8%).(4) They divided into ischemic type in182eyes(52.8%), and non-ischemic type in163eyes (47.2%).(5) Treatment efficiency: Theeffective rate was51.3%in CRVO,66.3%in BRVO,65.0%in HRVO; The effective ratewas51.3%in ischemic types,66.3%in non-ischemic types; the effective rate was77.2%in types of timely and effective treatment in7days,more than7days after treatment was29.4%.(6) The initial VA and prognosis: There was close relationship between initial VAand visual prognosis (2were68.370,39.684,11.753; P were <0.001,<0.001,<0.05).(7)Complications of RVO were cystoid macular edema (CME)(46.4%), neovascularization(21.6%), vitreous hemorrhage (21.6%), neovascular Glaucoma(4.3%).(8) Low vision andthe rate of blindness in RVO: According to the obstruction site of the various types ofRVO with low vision and blind rate, the difference was significant (χ2were7.478,21.420; P <0.05,<0.001); according to the type of ischemic or not ischemic, the difference wasstatistically significant (χ2=30.998,27.460, P were <0.001,<0.001).(9) Low visioncaused by CME was33.1%, and RNV was9.6%,blindness was12.5%, and RNV was13.7%. Conclusion: The rate of blindness of RVO is high, and the visual prognosis ofischemic type was worse. Systemic risk factors in RVO may be hypertension,atherosclerosis, increased blood viscosity, diabetes, glaucoma; local risk factors may beassociated with intraocular pressure (IOP), diurnal variation of intraocular pressuredifference and the axial. There was close relationship between the level of initial VA andvisual prognosis. CME, RNV, and NVG are important causes of blindness.