Magnetic Navigation System And CT Roadmap Assisted Percutaneous Coronary Intervention

Objectives:The aim of this study was to compare the MNS and CT roadmap assisted PCI versus conventional PCI regarding the difference of contrast usage,X-ray exposure, and procedure success.Background:Computer tomography (CT) coronary angiography has been successfully integrated with the magnetic navigation system(MNS)to facilitate a roadmap assisted percutaneous coronary intervention(PCI)for coronary artery disease. But the priority of this new approach of PCI has not yet been fully investigated.Methods:Thirty Eight patients with stable coronary artery disease were enrolled in the MNS group.Targeted vessels from pre-procedure CT coronary angiography were extracted, reconstructed, and finally transferred to the live fluoroscopic screen as roadmaps. Another38patients within the same study period were recruited in the conventional group, matched with the MNS group by the vessel and lesion type base on ACC/AHA criteria.Results:The contrast usage for guidewire crossing was significantly lower in the MNS group than that in the conventional group [0.0(0.0,3.0) vs.5.0(3.1,6.8) mL; P0.001], with zero contrast usage in25of the44guidewire placements in the MNS group,but in none of the conventional group. The radiation dosage for guidewire crossing in MNS group was also significantly lower than that in the conventional group [235.8(134.9,455.1) vs.364.4(223.4,547.2) μlGym2; P=0.033].All the enrolled vessels were successfully intervened in both MNS and conventional groups.Conclusions:Compared to conventional PCI, the MNS and CT roadmap assisted PCI can reduce contrast usage and radiation dosage for guidewire crossing during the process of coronary intervention.