Clinical Study On Different Dosage Forms Of NingXinZhiHan Decoction’s Influence To The Hypertension Accompanied With Spontaneous Sweat And Night Sweat(YinXuHuoWang Type)

Objective: To observe the curative effect of different dosage forms ofNingXinZhiHan Decoction to the HBP accompanied with Spontaneous Sweat and NightSweat of YinXuHuoWang Type,and to explore its mechanism,and to contrast its differenceof different forms.Methods:In the clinical study,Randomized principles,90patientsconforming to standard were divided into control group(30cases),decoction group(30cases)and paste group(30cases).The control group was treated only by conventional westernmedicine,while the decoction group was added to the NingXinZhiHan Decoction and thepaste group was added to the paste dosage forms of NingXinZhiHan Decoction.10dayswas a course of treatment.The main clinical symptom,resting heart rate,mean arterialpressure(MAP)and life quality were observed before and after treatment.Results:In thedecoction group and paste group,the total effective rate of meliorating symptoms and theremarkable rate were respectively93.4%,36.7%and96.6%,33.3%.They were nosignificant difference(p＞0.05),but significant different comparing with the controlgroup(p＜0.05);Resting heart rate of the two groups was all improved,and no significantdifference(p＞0.05),but significant different comparing with the control group(p＜0.05);there was no difference of MAP improves in three groups(p＞0.05).Scores of quality oflife improved in decoction group and paste group,and were better than the control group inthe psychological field(P<0.05);the two groups have no difference(p＞0.05). Conclusion:NingXinZhiHan Decoction is an effective medicament of treating Hypertensionaccompanied with Spontaneous Sweat and Night Sweat of YinXuHuoWang Type. The treatment effective of decoction group and paste group was similar,and was better than thecontrol group.