Tha Characteristics Of Dark-Adapted And Light-Adapted Oscillatory Potentials In Human Electroetinogram

Purpose: Electroretinogram (ERG) is the one of objective means to detectretinal functions. ERG oscillatory potentials (OPs) are indicators of theinner retinal function. However, only mixed-OPs driven by cones and rodsare used in clinical service and research. We characterized and compareddark-adapted and light-adapted OPs in human subjects.Methods: Dark-and light-adapted ERG of24normal eyes recorded from47consecutive cases aged22to30were studied. The frequency spectra ofextracted dark-adapted OPs and light-adapted OPs were analyzed by a fastFourier transform. The peak frequency, latency and the total power of theOPs were determined. Mann Whitney test was applied to determine wherethere were significance between the dark-adapted and the light-adaptedOPs.Results: The averaged peak frequency, latency and power of thedark-adapted OPs were125.3±9.93（Hz）,41.7±3.56(ms),9.25±5.55(V*s)2. The peak frequency,latency and power of light-adaptedOPs were79.5±6.79（Hz）,50.8±5.36ms,3.56±2.18(V*s)2. There were significant difference in peak frequency, latency and power betweendark-and light-adapted OPs(P<0.05).Conclusion: Compared to dark-adapted OPs characterize，light-adapted thepeak frequency and power is lower；the latency is longer.This research laya foundation for applying and analyzing OPs in clinical.