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Effect Of Bushen Huoxue Shujin Decoction On Cervical Intervertebral Disc Degeneration

Posted on:2013-11-22Degree:MasterType:Thesis
Country:ChinaCandidate:H ZhangFull Text:PDF
GTID:2234330374451380Subject:Orthopedics scientific
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Objective:In the clinical and animal model, and investigate the effect of Bushen Huoxue Shujin decoction on cervical intervertebral disc degeneration.Methods:Taking Of20cases with axial cervical pain, all patients were had been given Bushen Huoxue Shujin decoction a week, observe many clinical index such as TCM(Traditional Chinese Medicine) symptoms, Cervical spondylosis cervical functional score, VAS and SF-36health questionnaire merger neck disability index in2-course treatment, collecting relevant data materials to compare and analysis it by statistical methods, thus obtain the nourishing liver and kidney for activating blood circulation Bushen Huoxue Shujin decoction’s exact effect of results. Using the damage of the cervical intervertebral disc method of fiber ring made cervical disc degeneration model on the BoZa goats,.By applying the organization morphological observation, verify the success of the model. Postoperative oral the extract of Bushen Huoxue Shujin decoction, A group of control group, and group B for low dose group, for high dose group of group C, after2months to death and remove the cervical intervertebral disc, using histology, imaging methods, observe the degeneration of cervical intervertebral disc.Results:The effective rate was90.0%to axial cervical pain, which was to be treatment by Bushen Huoxue Shujin decoction. Before and after treatment were compared with the TCM(Traditional Chinese Medicine) cervical pains, Cervical spondylosis cervical functional score, VAS and SF-36health questionnaire merger neck disability index in2-course treatment, acrosss the T test, P value were less than0.05, Before and after treatment that are significant on TCM(Traditional Chinese Medicine) cervical pains, Cervical spondylosis cervical functional score, VAS and SF-36health questionnaire merger neck disability. Be compared with the disc degeneration in histologic before and after the experiment, neuroimaging studies are significant (P value were less than0.05), success through the damage of the cervical spine fiber ring sheep method developed cervical disc degeneration of animal model. Low dose group and high dose group of intervertebral disc disease compared with the control have improved, it makes clear that Bushen Huoxue Shujin decoction. paly a process role in the suppression and delay on the degeneration of cervical intervertebral disc.
Keywords/Search Tags:cervical spondylosis, axial cervical pain, cervical intervertebral disc, degeneration, animal model, Bushen Huoxue Shujin Decoction
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