Effects And Analysis Of Phytolacca Therapy On Damp-heat Of Edema In Nephritic Syndrome

Objetive:Observe the effects, side effect and dosages-effect relationship of two doses(conventional dose and small dose) Phytolacca therapy on Damp-heat of edema in nephritic syndrome, appraise to its validity and security, in order to guide the clinical treatment.Methods:In this study,30example patients with nephritic syndrome edema damp-heat are divided into2groups, in the ratio of1:1,15patients with conventional dose and15patients with small dose. Treatment for7days. Observe the24-hour urine, body weight, feces, edema grade, side effect before and after treatment. The statistics were treated by statistical package SPSS17.0. Measurement datas were described with mean±standard deviation (X±S). The main measurement datas before and after treatment was compared with matched-pairs t-test. comparison between groups use independent sample-t-test. Enumeration data were chi-square tested and P<0.05for statistical significance.Results:(1) The efficiency of conventional dose group is46.7%, the small dose60.0%. The two groups are no significant difference in efficacy.(2) In the two groups, the symptom score improved obviously, but have no significant differcnces(P>0.05).(3) The safety index before and after treatment have no significant difference both of the group (P>0.05).Conclusion:Both of the treatment of conventional dose and small dose can improve clinical symptoms and physical signs, but no significant differences in purgation and diuresis. The conventional dose and small dose of Phytolacca in treatment of nephritic syndrome is safe.