Children’s Hemophagocytic Syndrome:a Case Report And Review Of The Literature

OBJECTIVE:Improve the young doctor, s knowledge and accumulation xperience on diagnosis and treatment of hemophagocytic syndrome. METHODS:Report a case of a children’s hemophagocytic syndrome include it is Clinical manifestations、laboratory、diagnosis and treatment, and review of the literature. DESIGN:Case report. PATIENT(S):A8-year-old male patient was admitted to our hospital complaining of fever、Systemic ecchymosis、 hepatosplenomegaly、pancytopenia、Liver function is serious damage。Comprehensive of children’s laboratory tests, fit to the diagnosis standard of hemophagocytic syndrome.NTERVENTION(S):At start with the treatment of positive resist infection、infusion plasma and red blood cells、immunoglobulin(IVIG)、corticosteroids and Symptomatic treatment, the patient’s condition get beter. But after the upper respiratory tract infection, Clinical symptoms and signs increase again,In the above treatment on the basis of add a Vp-16chemotherapy, Soon the illness gets control and the index of basic laboratory returned to normal. But again after the infection, clinical symptom is the previous aggravating, continue to the original plan for treatment.RESULT(S):the effect of treatment is poor, Parents give up continue to treatment in our hospital.CONCLUSION(S):hemophagocytic syndrome is a rare malignant diseases of blood, Progress fast,and have a highdeath rate. At the same time of early control basic diseases,Positive immune-chemotherapy treatment is more appropriate treatment.