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The Application Value Of Ultrasonic Micropure System In The Diagnosis Of Breast Solid Benign And Malignant Tumor

Posted on:2013-08-19Degree:MasterType:Thesis
Country:ChinaCandidate:X K LiFull Text:PDF
GTID:2234330371483908Subject:Medical imaging and nuclear medicine
Abstract/Summary:PDF Full Text Request
Objective:Through ultrasonographic feature analysis of breast solid lumps by usingultrasonic "fireflies"(micropure system) imaging system, to evaluate the system’s capacityof the tiny calcification detection, and to illustrate the value for breast cancer diagnosis.Methods:Randomly selected121mass of the hospital confirmed115cases of femalepatients with breast solid tumor treatment by surgery or biopsy, observe the display cases ofmicrocalcification by molybdenum target X-ray, conventional ultrasonic and the Ultrasonicmicropure imaging system checks respectively. Contrast microcalcifications display ofmolybdenum target X-ray, conventional ultrasonic group and micropure system for theinspection group. Combined with the pathologic result, three groups of diagnosis of breastsolid benign and malignant tumor were analyzed. Build the ROC curves, and calculate thearea under the curve. Observe and analyze the characteristics of distribution of the threegroups of the microcalcifications. Comparative analyze the results of Molybdenum targetX–ray and conventional ultrasonic examination of the breast neoplasm BI-RADS gradingafter the micropure system analysis. By using sonogram of the micropure imaging system,calculate the largest micro calcification display number per unit area (N/S), calculate thesensitivity, specificity and accuracy of benign and malignant tumors, and obtain the optimumvalues of as the auxiliary diagnostic criteria for benign and malignant boundaries. Thestatistical software used in this study is SPSS13.0.counting material used chi-square test,with P <0.05with a statistical significance.Results:121cases of mammary gland real venereal disease pathology results: malignant cases68, and infiltrating ductal carcinoma48, infiltrating lobular carcinoma16, adenocarcinoma2,dysplasia2, benign53cases, including fiber adenoma23, adenopathy16, intraductalpapilloma2, breast proliferative lesion12.Ultrasonic micropure imaging system that the microcalcification in77,malignant tumorshows the microca-lcification in65, benign tumors show the microcalcification in12,malignant neoplasm is the microcalcification local concentration distribution of38, scatteredover27, benign neoplasm is the microcalcification local concentration distribution of3,scattered over9, the BI-RADS classification, level227, level333, level449, level512. Molybdenum target X line found the microcalcification59, malignant tumor shows themicrocalcification48, benign tumor shows the microcalcification11, malignant neoplasm isthe microcalcification local concentration distribution of32, scattered over16, benignneoplasm is the microcalcification local concentration distribution of2, scattered over9, theBI-RADS classification, level232, level336, level444, level59.Conventional ultrasonic found the microcalcification48,malignant tumor shows themicrocalcification42, benign tumor shows the microcalcification6, conventional ultrasonicmalignant neoplasm is the microcalcification local concentration distribution of27, scatteredover15, benign neoplasm is the microcalcification local concentration distribution of2,scattered over4, the BI-RADS classification, level229, level337, level445, level510.Ultrasonic micropure imaging system detection the microcalcification in77, thedetection rate is63.64%, molybdenum target X-ray detection59, the detection rate is48.76%, the conventional ultrasonic detection48, the detection rate is39.67%, and theUltrasound micropure imaging system that the microcalcification significantly higher thanthe ability of molybdenum target X line and conventional ultrasonic, the difference wasstatistically significant (P <0.05). Mammography X-ray detection and Ultrasonic micropureimaging system was not detected the microcalcification3.And through to the pathological clear the breast neoplasm micro calcification analysis,Ultrasonic micropure imaging system in good no matter, malignant tumor of the detectionrate is better than the microcalcification molybdenum target X line and conventionalultrasonic, Ultrasonic micropure imaging system, molybdenum target X line and conve-ntional ultrasonic detection rate of malignant neoplasm micro calcification is95.59%,70.59%and61.76%respectively, comparative differences apparent, was statisticallysignificant (P<0.05), benign neoplasm micro calcification detection rate of22.64%,20.75%and11.32%respectively, Ultrasonic micropure imaging system, molybdenum target X lineand conventional ultrasonic, compared with statistical significance was found between(P<0.05), but Ultrasonic micropure imaging system and molybdenum target X line,compared with no obvious difference, not statistically significant (P>0.05).Inside the breast neoplasm of the microcalcification distribution characteristics ofmorphology analysis, malignant tumor in the microcalcification local concentration distri-bution, benign tumors in the microcalcification scattered, and the amount is less.Three kinds of imaging examination of all breast solid the mass line BI-RADSclassification, the analysis we found molybdenum target X line and conventional ultrasonic2, 3level is the number of ultrasonic micropure imaging system, and4,5stage number is less,so that the ultrasonic micropure imaging system improves the ability of BI-RADSclassification. Level3benign may big, suggest short-term follow-up, and the level4forsuspicious malignant, consider the biopsy, is divided into level3or the level4, basic decidedthe mass of the good and the evil tendency, in clinical is very important. This studymolybdenum target X line BI-RADS classification for level3of36lesions in ultrasonicmicropure imaging system checks, there are8lesions tips for the level4, pathological return4for breast cancer. Conventional ultrasonic BI-RADS classification for3levels of37lesionsin ultrasonic micropure imaging system checks, there are6lesions tips for the level4,pathological return3for breast cancer. Further shows the ultrasonic micropure imagingsystem for BI-RADS classification to mammary gland solid benign and malignant tumor ofthe importance of identification.Ultrasonic micropure imaging system, molybdenum target X line, conventionalultrasonic imaging diagnosis three solid mass of mammary gland sensitivity and specificityof calculation, constructing the ROC curves, the area under the curve were0.898,0.728and0.820, and between the three difference have statistical significance (P <0.05).According to the Ultrasonic micropure imaging system of unit area biggest shows themicrocalcification number (N/S) and pathological results relatively than analysis method, thesensitivity and specificity. Constructing ROC curves, approximately up to index, whenvalues for2.5, high sensitivity and specificity, were77.9%,92.5%,, that number for onlyinteger, we think that when values for3, the diagnosis of high accuracy degree ofmalignancy.Conclusions:1.Ultrasonic micropure imaging system on the show was significantly higher than therate of calcification molybdenum target X line and conventional ultrasonic inspection.2.Ultrasonic micropure imaging system has helped improve the ability of BI-RADSclassification.3.Ultrasonic micropure imaging system under the ultrasonographic unit area themicrocalcification shows the largest number (N/S), when the value of3, as breast solidbenign and malignant tumor of the boundary boundaries.4.Ultrasonic micropure imaging system as a new imaging examination method, caneffectively improve the diagnosis of breast malignant tumor.
Keywords/Search Tags:Breast solid lumps, Ultrasonic micropure imaging system, micro calcification
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