The Curative Effect Comparison Between Hemodialysis And Continuous Ambulatory Peritoneal Dialysis On End Stage Diabetic Nephropathy

Background：Diabetes has become the incidence of the year, diabetescommon complication, diabetic nephropathy will become a major impact onhuman health. End stage diabetic complications are more complex, and thetreatment is still exist for lack of understanding, experience of other problems.Objective: Compare the curative effect between hemodialysis(HD)andcontinuous ambulatory peritoneal dialysis(CAPD)on end stage diabeticnephropathy. Provide better treatment for patients.Materials and Methods: A retrospective study of the clinical data of42case of end stage diabetic nephropathy in our hospital tremendously fromJanuary2008to December2011. Patients were divided into hemodialysisgroup and peritoneal dialysis group according to dialysis way. Compare thegeneral condition， biochemical indicator and complications between twogroups from the initial time to the following-up one year.Results:(1)Initiating dialysis, between the two groups diastolic bloodpressure, systolic blood pressure, body weight and urine output were notsignificantly difference (P>0.05),1year after the dialysis, there were obviousdifference (P <0.05)in systolic blood pressure and urine output.(2)Biochemical indicators：The two groups after treatment, the level of TG andTC of CAPD group was higher than the HD group, there were significantdifference (P <0.05)；The level of TP and ALB in HD group was higher thanCAPD group, there were significant difference (P <0.05).(3)After a year anddialysis, residual renal function of two group:HD group was (6.58±0.52) ml/min, CAPD group was (7.43±0.82) ml/min, indicating that CAPD is conduciveto the protection of the residual renal function；(4)Patients of HD group developed hypertension significantly increased than CAPD group. Sevenpatients infected in CAPD group, much higher than HD group (P <0.05), andgive priority to peritonitis.Conclusion: HD and CAPD treatment of diabetic nephropathy is twokinds of effective way, can achieve similar dialysis sufficiency. CAPDcompared with HD, have relatively stable hemodynamics, and can betterprotection of residual renal function, but easy to occur on lipid metabolismdisorders and malnutrition. Thus, for the clinical ESDN replacement therapy,should not only be limited to a kind of alternative therapy, but should beaccording to the specific conditions of dialysis patients choose alternativetherapy.