Treatment Of Benign Breast Tumor With Ultrasound-Guided Radiofrequency Abiation:perliminary Clinical Study

Objective: To explore availability, safety, efficacy, clinical outcomes andto gain operation experiences of benign breast mass treated byultrasound-guided Radiofrequency Ablation (RFA), with an attempt to offer analternative approach to minimally invasive surgery for breast mass which isbenign that confirmed by pathology.Methods: Collect the medical records of50female patients with benignbreast mass who underwent RFA in China-Japan Union Hospital affiliated withJilin University from June2011to May2012. They had no history of breastsurgery but complained with varying degrees of breast pain. Before RFA thepatients were checked with the following steps: physical examination, breastspecialist examination, breast B type ultrasonic examination on breast, liver andkidney function test, blood coagulation function test, immunoassay test,Tumor radionuclide scanning and core needle biopsy.32cases were consideredas solid mass and18cases took into account with cystic mass byultrasonoscopy，all of which have clear boundary, regular shape, no infiltrationof surrounding tissues, and there was no calcification or rich blood flow in theinterior and periphery of the masses and axillary metastatic lymph nodes wereabsent. Hepatic and renal function and blood coagulation were all within thenormal reference limits. All cases were benign breast masses confirmed bypathology.On the basis of subjective descriptions of echography from US physician,masses were divided into solid and cystic. All patients had a routine preparationbefore RFA and have been told possible risks and responses which contained the following complications such as hematoma formation, infection andpossibility of recurrence.All patients took a supine position with the upper limbs at abduction.Ultrasonoscopy was taken to recheck the position, size and shape of the mass,as well as the blood flow in the interior and periphery of the mass and whetherthere were calcification and axillary metastatic lymph nodes or not. Thedistance of the tumor between the chest wall and skin, the puncture point, depthof needle insertion, needle direction and angle were defined carefully.After anesthesia, under realtime US-guidance, the RFA needle active tipinserted into the center of the mass, then began the ablation.80℃、85℃、90℃、95℃were selected respectively，lasting for5minutes. Ablation was consideredcompleted when the total mass and its periphery was filled entirely withhigh-echogenic microbubbles. After RFA, Surgical removal of parts were sentfor pathological examination instantly.Results: Results of radiofrequency ablation at different temperatures forthe different nature of the tumor.Conclusion：1.Ultrasound-guided radiofrequency ablation is available forthe treatment of breast tumor because of its feasibility, safely, affectivity, and isworthy to be popularized in operation.2. The ablation range changes at different temperature, therefore, propertemperature should be selected according to different sizes of the tumor.3. RFA is more suitable for solid breast lesions. Because of in cysticlesions, the thermal solidification range is larger than the damage area.4. RFA is feasible and shows efficacy in solid mass with diameter lessthan4.0cm, while in cystic lesions,it is only suitable for the massed withdiameter less than2.0cm at90℃...