The Research For The Color Doppler’s Detecting The Correlation Between Early And Late Onset Severe Pre-eclampsia Fetus’ Umbilical Artery And Middle Cerebral Artery Velocity

Objective:to inquire into the hemodynamic changes in early and late onset severe pre-eclampsia fetus’ umbilical artery and middle cerebral artery flow, and the relationship with perinatal outcome.Methods:apply the Color Doppler into detecting37normal cases of pregnancy(gestation weeks are diameter more than34),31normal cases of pregnancy (28～34weeks of gestation),30cases of early onset severe pre-eclampsia and30cases of late onset severe pre-eclampsia patients’ fetal umbilical artery and middle cerebral artery’ ratio of peak systolic maximum velocity/end diastolic maximum velocity(S/D)、resistance index (RI)、at the same time, observe fetal intrauterine growth (the biparietal diameter、the length of femur) and record birth weight of new-born babies,1min Apgar score and the rates of fetal distress and low birth weight infants.Result:all the ratios between the S/D、RI of early onset severe pre-eclampsia fetal UA and the control group are higher than the one between late onset severe pre-eclampsia fetal UA and the control group, whose difference has statistical significance.(P<0.05). All the ratios between early onset severe pre-eclampsia fetal、MCA-RI、MCA-S/D and the control group are obviously lower than the ratios between late onset severe pre-eclampsia fetal UA and the control group, which has statistical significance.(P<0.05). All the ratios of early onset severe pre-eclampsia1min Apgar score(≤7),, and low birth weight infants are higher than those of late onset severe pre-eclampsia, which has statistical significance.(P<0.05)Conclusion:1、Compared with late onset severe pre-eclampsia fetal, early onset of severe pre-eclampsia during pregnancy has more clinical reference value which fetal UA-S/D、UA-RI、 MCA-RI、MCA-S/D and biparietal diameter, Apgar score for the evaluation of intrauterine fetal safety situation and predict neonatal birth outcome.2、On perinatal outcomes,compared with late onset severe pre-eclampsia fetal, early onset severe preeclampsia more likely to have low birth weight, and neonatal light, moderate and severe asphyxia.